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Current knowledge about and recommendations for ocular methicillin-resistant Staphylococcus aureus.

AbstractUNLABELLED:
Staphylococcus aureus is the most important and common pathogen that infects patients following cataract surgery, laser in situ keratomileusis, and photorefractive keratectomy. It is reported to be the second most common pathogen causing bacterial keratitis around the world. Of special concern are increasing reports of postoperative methicillin-resistant S aureus (MRSA) infection. For example, MRSA wound infections have been reported with clear corneal phacoemulsification wounds, penetrating keratoplasty, lamellar keratoplasty, and following ex vivo epithelial transplantation associated with amniotic membrane grafts. These and other data suggest that MRSA has become increasingly prevalent worldwide. In this article, we review the current medical literature and describe the current challenge of ocular MRSA infections. Recommendations are made based on an evidence-based review to identify, treat, and possibly reduce the overall problem of this organism.
FINANCIAL DISCLOSURE:
No author has a financial or proprietary interest in any material or method mentioned.
AuthorsFrancis S Mah, Richard Davidson, Edward J Holland, John Hovanesian, Thomas John, John Kanellopoulos, Neda Shamie, Christopher Starr, David Vroman, Terry Kim, ASCRS Cornea Clinical Committee
JournalJournal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 40 Issue 11 Pg. 1894-908 (Nov 2014) ISSN: 1873-4502 [Electronic] United States
PMID25442885 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2014 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.
Chemical References
  • Anti-Bacterial Agents
Topics
  • Anti-Bacterial Agents (therapeutic use)
  • Corneal Ulcer (diagnosis, microbiology, prevention & control)
  • Eye Infections, Bacterial (diagnosis, microbiology, prevention & control)
  • Humans
  • Methicillin-Resistant Staphylococcus aureus
  • Staphylococcal Infections (diagnosis, microbiology, prevention & control)

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