[Influence of magnesium deficiency correction on the effectiveness of bronchial asthma pharmacotherapy in children].

Abstract

We have performed 24-week open-labeled comparative randomized parallel-group study of the basic therapy efficacy of uncontrolled and partly controlled atopic asthma children with magnesium deficiency. The additional correction of magnesium deficiency increases the efficacy of atopic asthma basic therapy. It leads to more pronounced inhibition of local allergic inflammation in respiratory system, decreases the exacerbation frequency (9.5%, p = 0.02), and increases the number of asymptomatic days and the 12-week constant asthma control frequency (71.4%, p = 0.145) as compared to the group without magnesium deficiency correction.

• Authors: V I Petrov, I N Shishimorov, A A Perminov, I V Nefedov
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) Vol. 77 Issue 8 Pg. 23-7 ( 2014) ISSN: 0869-2092 [Print] Russia (Federation)
• PMID: 25335387 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Adrenal Cortex Hormones
• Magnesium

Topics

• Adolescent
• Adrenal Cortex Hormones (therapeutic use)
• Asthma (blood, complications, diet therapy, drug therapy)
• Child
• Dietary Supplements
• Erythrocytes (chemistry)
• Female
• Humans
• Magnesium (administration & dosage)
• Magnesium Deficiency (blood, complications, diet therapy, drug therapy)
• Male
• Treatment Outcome