Abstract | BACKGROUND:
Precocious puberty, as early physical development and low final height might lead to psychosocial problems. OBJECTIVE: To evaluate etiology and clinical feature of precocious puberty in a cohort of Iranian children. MATERIALS AND METHODS: In this case-series study, 44 girls and 8 boys with precocious puberty referred to Endocrine Reserch Centre (Firouzgar), Institute of Endocrinology and Metabolism (Hemmat Campus), were examined in a 10 years period of time. RESULTS: Mean age of girls and boys was 7.43±1.4 years and 5.8±2.1 years respectively. Most of the patients fell within the age category of 7-7.9 years old (40.9% for girls and 50% for boys). Patients, concerning etiology of precocious puberty were classified in three categories: 42.6% of patients had central precocious puberty ( CPP), including idiopathic CPP (87.5%) and neurogenic CPP (12.5%). 23.3% of patients had peripheral precocious puberty (PPP), including congenital adrenal hyperplasia (CAH) (42.8%), ovarian cysts (28.4%), McCune-Albright syndrome (14.2%) and adrenal carcinoma (14.2%). 34.1% of girls and 25% of boys had normal variant puberty including premature thelarche (57%), premature adrenarche (38%) as well as premature menarche (4.7%l). CONCLUSION:
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Authors | Farzaneh Rohani, Shadab Salehpur, Fatemeh Saffari |
Journal | Iranian journal of reproductive medicine
(Iran J Reprod Med)
Vol. 10
Issue 1
Pg. 1-6
(Jan 2012)
ISSN: 1680-6433 [Print] Iran |
PMID | 25242967
(Publication Type: Journal Article)
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