Comparative effect of fluoride, essential oil and chlorhexidine mouth rinses on dental plaque and gingivitis in patients with and without dental caries: a randomized controlled trial.

Abstract

OBJECTIVES:

The objective of this study was to compare the effectiveness of fluoride, essential oil (EO) and chlorhexidine (CHX)-containing mouth rinses on dental plaque and gingivitis and to compare their relative efficacy in patients with and without dental caries.

MATERIAL AND METHODS:

A randomized, controlled, double- blind, crossover clinical trial was conducted for a period of 8 weeks. Thiry-six qualifying subjects, aged 12-44 years, were included in the study. Subjects were divided into caries and caries-free groups and were randomly assigned to one of the following mouth rinse groups: fluoride; EO; CHX and saline as negative control. Subjects used their respective mouth rinse for a period of 7-days each with 1-week wash-out periods. Primary efficacy variables were Quigley-Hein plaque index (PI) and Loe and Silness gingival index.

RESULTS:

Fluoride and CHX mouth rinses showed significant reduction in plaque after use of mouth rinses (P < 0.05). However, no significant differences were observed with respect to each other in reducing gingivitis (P > 0.05). Further significant differences were found in reducing plaque and gingivitis in caries-free subjects in comparison to those with caries (P < 0.05).

CONCLUSION:

All the three mouth rinses significantly reduced plaque accumulation and gingivitis especially in caries-free subjects in comparison to those with caries, and amongst the three, fluoride and CHX proved to be more effective than EO mouth rinse.

• Authors: B R Charugundla, S Anjum, M Mocherla
• Journal: International journal of dental hygiene (Int J Dent Hyg) Vol. 13 Issue 2 Pg. 104-9 (May 2015) ISSN: 1601-5037 [Electronic] England
• PMID: 25040544 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
• Copyright: © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Chemical References

• Anti-Infective Agents, Local
• Cariostatic Agents
• Mouthwashes
• Oils, Volatile
• Placebos
• Fluorides
• Chlorhexidine

Topics

• Adolescent
• Adult
• Anti-Infective Agents, Local (therapeutic use)
• Cariostatic Agents (therapeutic use)
• Child
• Chlorhexidine (therapeutic use)
• Cross-Over Studies
• Dental Caries (complications)
• Dental Plaque (prevention & control)
• Dental Plaque Index
• Double-Blind Method
• Female
• Fluorides (therapeutic use)
• Follow-Up Studies
• Gingivitis (prevention & control)
• Humans
• Male
• Mouthwashes (therapeutic use)
• Oils, Volatile (therapeutic use)
• Periodontal Index
• Placebos
• Treatment Outcome
• Young Adult