Abstract | AIM: METHODS: Mice were treated with CCl4 for 8 weeks to induce fibrosis. Concurrently, mice received drinking water with or without 180 mg/L TCA. RESULTS: CONCLUSION: The data suggest that ASM is a critical signaling component in HSC for the development of liver fibrosis and represents an important therapeutic target.
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Authors | Ralph C Quillin 3rd, Gregory C Wilson, Hiroyuki Nojima, Christopher M Freeman, Jiang Wang, Rebecca M Schuster, John A Blanchard, Michael J Edwards, Chandrashekhar R Gandhi, Erich Gulbins, Alex B Lentsch |
Journal | Hepatology research : the official journal of the Japan Society of Hepatology
(Hepatol Res)
Vol. 45
Issue 3
Pg. 305-14
(Mar 2015)
ISSN: 1386-6346 [Print] Netherlands |
PMID | 24796378
(Publication Type: Journal Article)
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Copyright | © 2014 The Japan Society of Hepatology. |