Sedation and paralysis.

Abstract

Sedation is used almost universally in the care of critically ill patients, especially in those who require mechanical ventilatory support or other life-saving invasive procedures. This review will focus on the sedation strategies for critically ill patients and the pharmacology of commonly used sedative agents. The role of neuromuscular blocking agents in the ICU will be examined and the pharmacology of commonly used agents is reviewed. Finally a strategy for rational use of these sedative and neuromuscular blocking agents in critically ill patients will be proposed.

• Authors: Annop Piriyapatsom, Edward A Bittner, Jessica Hines, Ulrich H Schmidt
• Journal: Respiratory care (Respir Care) Vol. 58 Issue 6 Pg. 1024-37 (Jun 2013) ISSN: 1943-3654 [Electronic] United States
• PMID: 23709198 (Publication Type: Journal Article, Review)

Chemical References

• Hypnotics and Sedatives
• Neuromuscular Blocking Agents

Topics

• Algorithms
• Critical Care
• Critical Illness (therapy)
• Deep Sedation (adverse effects)
• Drug Monitoring
• Humans
• Hypnotics and Sedatives (administration & dosage, adverse effects)
• Neuromuscular Blocking Agents (administration & dosage, adverse effects)
• Paralysis (chemically induced)
• Respiration, Artificial (methods)
• Ventilator Weaning