Abstract | BACKGROUND: METHODS: Patients with head and neck cancer treated with radiation therapy (RT) from 2004 to 2010 who experienced neck spasms werereviewed. Radiation doses were generated for their sternocleidomastoid (SCM) muscles bilaterally. Unaffected SCMs were used as controls. RESULTS: Thirty-four patients reported neck spasms. Thirty had received definitive chemoradiation, and 4 had RT alone. Seven also had an ipsilateral neck dissection. Median time to onset was 23 months (range, 6-67 months). There were significantly higher radiation doses to the affected SCMs with a median of the mean dose to the affected and unaffected SCM of 62.3 Gy (range, 29-71 Gy) and 53.7 Gy (range, 27-65 Gy), respectively (p < .0001). Other dosimetric variables were also statistically significant but were highly correlated with the mean SCM dose. Neck dissection did not affect our results. CONCLUSION:
|
Authors | Klaudia U Hunter, Francis Worden, Carol Bradford, Mark Prince, Scott McLean, Gregory Wolf, Douglas B Chepeha, Avraham Eisbruch |
Journal | Head & neck
(Head Neck)
Vol. 36
Issue 2
Pg. 176-80
(Feb 2014)
ISSN: 1097-0347 [Electronic] United States |
PMID | 23559555
(Publication Type: Journal Article)
|
Copyright | Copyright © 2013 Wiley Periodicals, Inc. |
Topics |
- Adult
- Aged
- Chemoradiotherapy
(adverse effects)
- Female
- Follow-Up Studies
- Head and Neck Neoplasms
(therapy)
- Humans
- Male
- Middle Aged
- Neck Dissection
(methods)
- Neck Muscles
(radiation effects)
- Prospective Studies
- Radiotherapy Dosage
- Radiotherapy Planning, Computer-Assisted
- Radiotherapy, Adjuvant
(adverse effects)
- Risk Factors
- Severity of Illness Index
- Smoking
(adverse effects)
- Spasm
(diagnosis, etiology)
|