Abstract | OBJECTIVES: MATERIALS AND METHODS: This is a retrospective study over a period of 10 years (2001-2010) on 43 patients: 28 women and 15 men with a mean age of 39.3 years (range 16-68 years). The myasthenia gravis was confirmed by clinical, electromyographic data and the presence of antibodies to acetylcholine receptors. RESULTS: Computed tomography objectified thymic mass in 14 cases (32.5%) enlarged thymus without visible mass in eight cases (18.6%). All patients received anticholinesterase, cortico steroids in 25 cases and in three cases plasmapheresis was required. The surgical approach was total sternotomy (n=32 cases), cervicotomy (n=2), cervical and manubriotomy (n=1), a manubriotomy (n=3) and a thoracotomy in five cases (lateralised thymoma). All patients underwent a total thymectomy associated or not with resection of the tumour. Intensive Care Unit was necessary for at least 24h up to six days. The postoperative course was marked by a myasthaenic crisis (n=2) and respiratory failure (n=3) with a favourable outcome. The prognosis was marked by a complete remission in 14 cases, partial remission in 11 patients, stabilisation (n=16 cases) and increasing crisis in two patients. CONCLUSION:
|
Authors | Massine El Hammoumi, Adil Arsalane, Fayçal El Oueriachi, El Hassane Kabiri |
Journal | Heart, lung & circulation
(Heart Lung Circ)
Vol. 22
Issue 9
Pg. 738-41
(Sep 2013)
ISSN: 1444-2892 [Electronic] Australia |
PMID | 23548337
(Publication Type: Journal Article, Review)
|
Copyright | Copyright © 2013 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved. |
Chemical References |
|
Topics |
- Adolescent
- Adult
- Aged
- Autoantibodies
(blood)
- Electromyography
- Female
- Humans
- Male
- Middle Aged
- Myasthenia Gravis
(blood, pathology, physiopathology, surgery)
- Retrospective Studies
- Thymoma
- Thymus Gland
(metabolism, pathology, physiopathology, surgery)
|