Abstract |
Circulating immune complexes (CIC) rises in response to immunogens appearing in human body. An increasing of the CIC concentration is observed in allergies as well as many others diseases. As a result of inflammatory process localized within intracellular space heat shock proteins (HSP) may occur. The aim of work was the CIC levels estimation as well as CIC HSP-70 presence analysis in serum of smoking and non-smoking allergy sufferers. Serum from 12 smoking and 15 non-smoking patients were examined. Serum from 34 healthy persons constituted the control group. The level of CIC was established by Haskowa precipitation method. The identification of HSP-70 antigen within CIC was determined by Dot blot method. We discovered increased CIC levels in serum from smoking allergy sufferers in comparison with non-smokers. The highest percentage of HSP-70 presence within CIC was observed in smoking allergy sufferers.
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Authors | Ryszard Gołda, Grzegorz Przybylski, Wojciech Jóźwicki, Małgorzata Wyszomirska |
Journal | Przeglad lekarski
(Przegl Lek)
Vol. 69
Issue 10
Pg. 737-9
( 2012)
ISSN: 0033-2240 [Print] Poland |
Vernacular Title | Krazace kompleksy immunologiczne, białko szoku cieplnego w surowicach osób z alergia palacych tytoń--badania wstepne. |
PMID | 23421022
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Antigen-Antibody Complex
- Heat-Shock Proteins
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Topics |
- Adult
- Antigen-Antibody Complex
(blood)
- Heat-Shock Proteins
(blood)
- Humans
- Hypersensitivity
(blood, immunology)
- Middle Aged
- Reference Values
- Serum
(immunology)
- Smoking
(adverse effects, blood, immunology)
- Young Adult
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