Plasma free amino acid profiles of canine mammary gland tumors.

Abstract

The purpose of this study was to elucidate the relationship between plasma free amino acid (PFAA) levels and the clinical stages of mammary gland tumors (MGT) in dogs. PFAA levels in canines with malignant mammary tumors were decreased compared to those of healthy animals. The levels of aspartate and ornithine, in the dogs with tumor metastasis were significantly decreased when compared to those of dogs that did not have metastases. Results of this study indicate that PFAA levels could be a risk factor or biomarker for canine MGT metastasis.

• Authors: Kazuo Azuma, Tomohiro Osaki, Takeshi Tsuka, Tomohiro Imagawa, Saburo Minami, Yoshiharu Okamoto
• Journal: Journal of veterinary science (J Vet Sci) Vol. 13 Issue 4 Pg. 433-6 (Dec 2012) ISSN: 1976-555X [Electronic] Korea (South)
• PMID: 23271187 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Amino Acids
• Serum Albumin

Topics

• Age Factors
• Amino Acids (blood)
• Animals
• Body Weight
• Dog Diseases
• Dogs
• Female
• Mammary Neoplasms, Animal (blood, genetics)
• Neoplasm Metastasis (diagnosis, genetics)
• Neoplasm Staging (veterinary)
• Serum Albumin
• Sex Factors