Abstract | BACKGROUND/AIMS: METHODS: Among the 1,003 patients, who were identified to have colonic diverticulosis including sleeding by diverticulitis and diverticular bleeding coding search, 216 patients had diverculosis, and they were divided into two groups: one with diverticular bleeding, and the other without bleeding. We evaluated the potential risk factors for diverticular bleeding, based on age, gender, location of diverticulum, comorbidities related to atherosclerosis, smoking, alcohol and medications, and compared them between both groups. RESULTS: Among the 216 patients, we observed colonic diverticular bleeding in 35 patients (16.2%). The mean age of the bleeding group was significantly older than that of non- bleeding group. No difference was observed regarding gender ratio. Right colonic diverticula were common in both groups, but there were higher proportion of patients with bleeding in bilateral diverticuosis. Old age, bilateral diverticulosis, presence of atherosclerosis related diseases ( hypertension, diabetes mellitus, ischemic heart disease, obesity), use of aspirin, NSAIDs and calcium channel blocker, increased the risk of bleeding. In a multivariate analysis, use of aspirin and bilateral diverticulosis were identified as independent risk factors for colonic diverticular bleeding. CONCLUSIONS: Since the patients who took aspirin and/or had bilateral colonic diverticulosis increased the risk of bleeding from divertuculi. As such, caution and education of patients are required.
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Authors | Seungchul Suh, Pyoung Ju Seo, Hyunkyung Park, Cheol Min Shin, Hyun Jin Jo, Hyun Young Kim, Sang Hyub Lee, Young Soo Park, Jin Hyeok Hwang, Jin Wook Kim, Sook Hyang Jeong, Nayoung Kim, Dong Ho Lee, In Sung Song, Hyun Chae Jung |
Journal | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
(Korean J Gastroenterol)
Vol. 60
Issue 6
Pg. 349-54
(Dec 2012)
ISSN: 2233-6869 [Electronic] Korea (South) |
PMID | 23242017
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Anti-Inflammatory Agents, Non-Steroidal
- Calcium Channel Blockers
- Aspirin
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Topics |
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Anti-Inflammatory Agents, Non-Steroidal
(therapeutic use)
- Aspirin
(therapeutic use)
- Calcium Channel Blockers
(therapeutic use)
- Colonic Diseases
(etiology)
- Colonoscopy
- Diabetes Complications
- Diverticulum, Colon
(epidemiology)
- Female
- Gastrointestinal Hemorrhage
(epidemiology, etiology)
- Humans
- Hypertension
(complications, drug therapy)
- Logistic Models
- Male
- Middle Aged
- Myocardial Ischemia
(complications)
- Obesity
(complications)
- Odds Ratio
- Risk Factors
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