Nutrition support and infections associated with hepatic resection and liver transplantation in patients with chronic liver disease.

Abstract

Malnutrition is common in liver cirrhotic patients who will undergo liver resection or liver transplantation. A precise evaluation of their nutrition status is thus difficult because of the presence of ascites and the edema caused by their impaired protein synthesis. Both perioperative enteral and parenteral nutrition have benefits in reducing the morbidity and mortality of liver surgery, and in general, oral nutrition supplements are recommended. Branched-chain amino acids (BCAAs) promote protein and glycogen synthesis and regulate immune system function. Synbiotics, a combination of pro- and prebiotics, is reported to enhance immune responses. Oral nutrition support with BCAAs, synbiotics, and an immune-enhancing diet have a beneficial effect on preventing the perioperative infections associated with hepatic resection or liver transplantation.

• Authors: Toshiro Masuda, Ken Shirabe, Shohei Yoshiya, Rumi Matono, Kazutoyo Morita, Naotaka Hashimoto, Toru Ikegami, Tomoharu Yoshizumi, Hideo Baba, Yoshihiko Maehara
• Journal: JPEN. Journal of parenteral and enteral nutrition (JPEN J Parenter Enteral Nutr) 2013 May-Jun Vol. 37 Issue 3 Pg. 318-26 ISSN: 1941-2444 [Electronic] United States
• PMID: 22898793 (Publication Type: Journal Article, Review)

Chemical References

• Amino Acids, Branched-Chain
• Prebiotics

Topics

• Amino Acids, Branched-Chain (administration & dosage)
• Bacteremia (complications, microbiology, prevention & control)
• Dietary Supplements
• Hepatectomy
• Humans
• Liver (pathology, surgery)
• Liver Diseases (complications, physiopathology, surgery)
• Liver Transplantation
• Malnutrition (complications, diet therapy, physiopathology)
• Nutritional Status
• Nutritional Support (methods)
• Postoperative Complications (microbiology, prevention & control, surgery)
• Prebiotics
• Probiotics (administration & dosage)
• Synbiotics