Squamous cell carcinoma-antigen for detection of squamous cell and mucoepidermoid carcinoma after primary treatment: a preliminary report.

Abstract

This study evaluated the efficacy of using the periodic measurement of the serum level of squamous cell carcinoma antigen (SCC-antigen) for determining the local recurrence and/or metastasis of squamous cell and mucoepidermoid carcinomas after primary treatment. It was found that at the time of clinical recognition of recurrence, the SCC-antigen level was normal, but metastasis to regional lymph nodes or to remote organs generally was accompanied by an increase of SCC-antigen. Changes in the SCC-antigen level with mucoepidermoid carcinoma seemed to be less sensitive than with squamous cell carcinoma.

• Authors: Y Yoshimura, M Oka, T Harada
• Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (J Oral Maxillofac Surg) Vol. 48 Issue 12 Pg. 1288-92; discussion 1292-3 (Dec 1990) ISSN: 0278-2391 [Print] United States
• PMID: 2231147 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antigens, Neoplasm
• Biomarkers, Tumor

Topics

• Aged
• Antigens, Neoplasm (blood)
• Biomarkers, Tumor (blood)
• Carcinoma (diagnosis, immunology, secondary, therapy)
• Carcinoma, Squamous Cell (diagnosis, immunology, secondary, therapy)
• Head and Neck Neoplasms (diagnosis, immunology, secondary, therapy)
• Humans
• Male
• Middle Aged
• Neoplasm Recurrence, Local (diagnosis, immunology)
• Prognosis