Signal amplification by magnetic force on polydiacetylene supramolecules for detection of prostate cancer.

Abstract

A method in which a permanent magnet is introduced onto polydiacetylene (PDA) vesicle chips is introduced for enhancement of the fluorescence of PDA vesicles. This strategy can be applied to general antibody-based PDA vesicle chips to detect clinically important biomarkers for disease diagnosis.

• Authors: Il Kyoung Kwon, Min Sun Song, Sang Ho Won, Seung Phill Choi, Moonil Kim, Sang Jun Sim
• Journal: Small (Weinheim an der Bergstrasse, Germany) (Small) Vol. 8 Issue 2 Pg. 209-13 (Jan 23 2012) ISSN: 1613-6829 [Electronic] Germany
• PMID: 22081508 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chemical References

• Antibodies, Immobilized
• Antibodies, Monoclonal
• Polyacetylene Polymer
• Polymers
• alpha 1-Antichymotrypsin
• alpha-Macroglobulins
• Polyynes
• polydiacetylene
• Biotin
• Streptavidin
• Prostate-Specific Antigen

Topics

• Antibodies, Immobilized
• Antibodies, Monoclonal
• Biosensing Techniques (methods, statistics & numerical data)
• Biotin
• Fluorescence
• Humans
• Magnetic Phenomena
• Male
• Microscopy, Electron, Scanning
• Polyacetylene Polymer
• Polymers
• Polyynes
• Prostate-Specific Antigen (blood)
• Prostatic Neoplasms (blood, diagnosis)
• Streptavidin
• alpha 1-Antichymotrypsin (blood)
• alpha-Macroglobulins (analysis)