HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Severe iatrogenic airway obstruction due to lingual lymphangioma].

Abstract
Lymphangioma of the tongue is a rare and benign tumour involving congenital and cystic abnormalities derived from lymphatic vessels. Treatment modalities include surgery and a large number of different intralesional injections of sclerosing agents. Presently, OK-432 (Picibanil(®)) is the preferred sclerosant and when administered intralesionally will result in inflammation, sclerosis, and cicatricial contraction of the lesion. We report a case of microcystic lymphangioma of the tongue in a 5-year-old boy treated with an intralesional injection of OK-432. In the immediate postoperative period, the patient suffered severe diffuse swelling, progressive upper airway obstruction with inspiratory stridor, and respiratory distress requiring emergency fiberoptic nasotracheal intubation. Although OK-432 injections are found to be safe and effective as a first line of treatment for lymphangiomas, local swelling with potentially life-threatening airway compromise should be anticipated, especially when treating lesions near the upper airway.
AuthorsA Segado Arenas, J-C Flores González, F Rubio Quiñones, S Quintero Otero, A Hernández González, S Pantoja Rosso
JournalArchives de pediatrie : organe officiel de la Societe francaise de pediatrie (Arch Pediatr) Vol. 18 Issue 9 Pg. 983-6 (Sep 2011) ISSN: 1769-664X [Electronic] France
Vernacular TitleObstruction iatrogène sévère de la voie aérienne par un lymphangiome lingual.
PMID21820291 (Publication Type: Case Reports, English Abstract, Journal Article)
CopyrightCopyright © 2011 Elsevier Masson SAS. All rights reserved.
Chemical References
  • Sclerosing Solutions
  • Picibanil
Topics
  • Airway Obstruction (etiology, surgery, therapy)
  • Child, Preschool
  • Humans
  • Injections, Intralesional
  • Intubation, Intratracheal
  • Lymphangioma, Cystic (complications, drug therapy)
  • Male
  • Picibanil (administration & dosage, adverse effects)
  • Sclerosing Solutions (administration & dosage, adverse effects)
  • Tongue Neoplasms (complications, drug therapy)
  • Tracheostomy
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: