Abstract | BACKGROUND: METHODS: A 72 year old hypertensive patient with palpitations and significant exercise intolerance due to dyspnea was evaluated with echocardiography, thallium stress testing and cardiac catheterization. Holter monitor data prior to, and after institution of ranolazine 1000 mg twice daily was compared. Patient tolerance and sense of well being after ranolazine was assessed. RESULTS: Significant LVH was noted and obstructive coronary artery disease was ruled out by cardiac catheterization. Within two hours of the initial dose of ranolazine a marked decrease in ventricular ectopy was observed. Ventricular ectopy on Holter monitor decreased approximately 12 fold (23.8% of beats to1.9%) while supraventricular ectopy decreased approximately 7 fold (5.3% of beats to 0.8%). The decrease in ectopy was associated with an improved sense of well being. CONCLUSION:
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Authors | David K Murdock, Jeffrey W Kaliebe |
Journal | Indian pacing and electrophysiology journal
(Indian Pacing Electrophysiol J)
Vol. 11
Issue 3
Pg. 84-8
(May 01 2011)
ISSN: 0972-6292 [Electronic] Netherlands |
PMID | 21556158
(Publication Type: Journal Article)
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