A randomized, controlled trial on the effect of non-surgical periodontal therapy in patients with type 2 diabetes. Part I: effect on periodontal status and glycaemic control.

Abstract

AIM:

the purpose of the present study was to assess the effect of non-surgical periodontal therapy on glycaemic control of type 2 diabetes patients with moderate-to-severe periodontitis.

MATERIALS AND METHODS:

this was a randomized, controlled clinical trial of patients with type 2 diabetes. A total of 60 patients with moderate-to-severe periodontal disease were assigned to either a periodontal treatment arm, consisting of scaling and root planing (intervention group [IG]), or a delayed treatment arm that received periodontal care after 6 months (control group [CG]). Periodontal parameters and glycosylated haemoglobin (A1C) were evaluated at 1, 3 and 6 months.

RESULTS:

all periodontal parameters improved significantly in the IG. A1C levels decreased statistically significantly more in the IG versus the CG (0.72%versus 0.13%; p<0.01) independently of other confounders.

CONCLUSIONS:

this study provides evidence that periodontal treatment contributes to improved glycaemic control in type 2 diabetes mellitus patients. Larger controlled trials are needed to confirm if this finding is generalizable to other populations of patients with type 2 diabetes.

• Authors: Panagiotis A Koromantzos, Konstantinos Makrilakis, Xanthippi Dereka, Nicholas Katsilambros, Ioannis A Vrotsos, Phoebus N Madianos
• Journal: Journal of clinical periodontology (J Clin Periodontol) Vol. 38 Issue 2 Pg. 142-7 (Feb 2011) ISSN: 1600-051X [Electronic] United States
• PMID: 21114680 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Blood Glucose
• Glycated Hemoglobin A

Topics

• Aged
• Blood Glucose (metabolism)
• Dental Scaling
• Diabetes Mellitus, Type 2 (blood, complications)
• Follow-Up Studies
• Glycated Hemoglobin (metabolism)
• Humans
• Male
• Middle Aged
• Periodontal Diseases (blood, complications, pathology, therapy)
• Periodontal Index
• Prospective Studies
• Severity of Illness Index
• Single-Blind Method
• Statistics, Nonparametric
• Treatment Outcome