Atopic dermatitis associated with HPV 38 lower leg verrucosis.

Abstract

We describe a 45-year-old woman with atopic dermatitis who presented with a progressive, papular eruption over her anterior lower legs that began 30 years earlier. Biopsy with polymerase chain reaction analysis revealed lichenified plane warts harboring human papillomavirus 38 DNA. No signs or family history of epidermodysplasia verruciformis existed. Local trauma from shaving, barrier dysfunction, and decreased cell immunity and interferon production associated with atopic dermatitis are likely responsible for this presentation of lower leg verrucosis.

• Authors: Elzbieta A Slodkowska, Joseph Schwartz, Peter L Rady, Stephen K Tyring, J Andrew Carlson
• Journal: The American Journal of dermatopathology (Am J Dermatopathol) Vol. 32 Issue 6 Pg. 610-3 (Aug 2010) ISSN: 1533-0311 [Electronic] United States
• PMID: 20520524 (Publication Type: Case Reports, Journal Article)

Chemical References

• DNA, Viral

Topics

• DNA, Viral (analysis)
• Dermatitis, Atopic (pathology, virology)
• Female
• Humans
• Leg
• Middle Aged
• Papillomaviridae (genetics, isolation & purification)
• Papillomavirus Infections (complications, pathology)
• Warts (complications, pathology)