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A patient with intractable posthypoxic myoclonus (Lance-Adams syndrome) treated with sodium oxybate.

Abstract
Posthypoxic myoclonus is a rare and devastating complication of near-fatal cardiopulmonary arrest. Despite treatment with available anti-myoclonic agents, some patients may recover cognitively but remain completely disabled by severe myoclonus. We report a 16-year-old patient with severe treatment-refractory posthypoxic myoclonus, which improved markedly with administration of the drug sodium oxybate.
AuthorsR Arpesella, C Dallocchio, C Arbasino, R Imberti, R Martinotti, S J Frucht
JournalAnaesthesia and intensive care (Anaesth Intensive Care) Vol. 37 Issue 2 Pg. 314-8 (Mar 2009) ISSN: 0310-057X [Print] United States
PMID19400500 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Sodium Oxybate
Topics
  • Adolescent
  • Electroencephalography
  • Heart Arrest (complications)
  • Humans
  • Hypoxia, Brain (complications)
  • Male
  • Myoclonus (drug therapy, etiology, physiopathology)
  • Sodium Oxybate (therapeutic use)
  • Syndrome

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