Abstract | BACKGROUND: METHODS: Serum PTH values were measured in Graves' patients with postoperative hypocalcemia, and those patients were followed postoperatively. RESULTS: Subtotal thyroidectomy was performed in 275 patients with Graves' disease. Their serum calcium levels were measured on postoperative day (POD) 1, and patients with transient postoperative hypocalcemia were treated with calcium and vitamin D supplementation and followed up. The amount of calcium and vitamin D supplementation was adjusted to keep the patient's serum calcium level within the normal range. Measurement of their serum intact PTH value on POD 1 revealed normal value in 18 patients, a below normal level in 22, and an above normal level in the other 2. During the follow-up period, the serum iPTH values remained normal in 12 patients, recovered to the normal level in 21 patients, and rose above the normal range in 9 patients. The serum iPTH values of all patients eventually reached the normal range during the follow-up period. A marked difference in preoperative serum alkaline phosphatase concentration was observed between the high-iPTH patients and the normocalcemic patients. CONCLUSIONS:
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Authors | Yukiko Yano, Mitsuji Nagahama, Kiminori Sugino, Kunihiko Ito, Koichi Ito |
Journal | World journal of surgery
(World J Surg)
Vol. 32
Issue 12
Pg. 2612-6
(Dec 2008)
ISSN: 0364-2313 [Print] United States |
PMID | 18836764
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Female
- Follow-Up Studies
- Graves Disease
(blood, surgery)
- Humans
- Hypocalcemia
(blood, etiology, therapy)
- Male
- Middle Aged
- Parathyroid Glands
(physiopathology)
- Parathyroid Hormone
(blood)
- Retrospective Studies
- Thyroidectomy
(adverse effects)
- Time Factors
- Treatment Outcome
- Young Adult
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