Abstract | OBJECTIVE: METHODS: RESULT: Compared with Group A, serum and renal MDA, serum Cr, BUN of Group B were significant increased (P <0.01), serum and renal SOD of Group B were significant decreased (P <0.01). After edaravone treatment, serum MDA, Cr and renal MDA of Group C were lower than those in Group B (P<0.01); Serum and renal SOD of group C were higher than those in Group B (P <0.01); Compared with Group B, BUN level of Group C had no significant change (P >0.05). The renal ultrastructure was greatly injured in Group B, meanwhile it was obviously ameliorated in Group C. CONCLUSION:
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Authors | Ge Zhang, Qiu-ping Xu, Hai-ying Huang |
Journal | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
(Zhejiang Da Xue Xue Bao Yi Xue Ban)
Vol. 37
Issue 3
Pg. 308-11
(05 2008)
ISSN: 1008-9292 [Print] China |
PMID | 18546537
(Publication Type: Journal Article)
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Chemical References |
- Malondialdehyde
- Superoxide Dismutase
- Edaravone
- Antipyrine
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Topics |
- Animals
- Antipyrine
(analogs & derivatives, therapeutic use)
- Edaravone
- Kidney
(blood supply)
- Male
- Malondialdehyde
(metabolism)
- Random Allocation
- Rats
- Rats, Sprague-Dawley
- Reperfusion Injury
(metabolism, prevention & control)
- Superoxide Dismutase
(metabolism)
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