Abstract | BACKGROUND: CASE REPORT: A 45-year-old woman with a classic form of DM of ten yearsn duration was evaluated. Clinical investigation revealed periorbital edema and violaceous erythema of the eyelids, Gottronns papules of the fingers, Gottronns sign on the elbows and malleoli, a plantar fissured, hyperkeratotic, and scaling eruption ("calloused feet"), ragged cuticles with dilated nail-fold telangiectasia, and gingival telangiectases. The patient fulfilled Bohan and Peterns criteria for the clinical, histological, EMG, and biochemical diagnosis of DM. Elevated titers of ANA (1:320) with a speckled pattern and anti Jo-1 antibodies were found in her sera by ELISA and Western blot. CONCLUSION: The recognition of subsets within the spectrum of DM characterized by certain clinical and serological features may be important. Because facial telangiectases are a recognized finding in this subset of patients, we suggest that gingival telangiectases might be a marker for the antisynthetase syndrome.
|
Authors | Lyubomir A Dourmishev, Assen L Dourmishev, Robert A Schwartz |
Journal | Acta dermatovenerologica Alpina, Pannonica, et Adriatica
(Acta Dermatovenerol Alp Pannonica Adriat)
Vol. 16
Issue 2
Pg. 67-72
(Jun 2007)
ISSN: 1318-4458 [Print] Slovenia |
PMID | 17992461
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Antibodies, Antinuclear
- Jo-1 antibody
|
Topics |
- Antibodies, Antinuclear
(blood)
- Dermatomyositis
(complications, immunology, pathology)
- Female
- Gingival Diseases
(etiology, pathology)
- Humans
- Middle Aged
- Skin
(pathology)
- Telangiectasis
(etiology, pathology)
|