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A double-blind clinical trial to compare the efficacy of an active based cream F14001 against a placebo non-active based cream for the treatment of pressure ulcers in a population of elderly subjects.

Abstract
A double-blind clinical trial was conducted to compare the efficacy of an active based cream against a placebo non-active based cream in the healing of superficial pressure ulcers in a population of geriatric hospital patients and residents in community nursing homes. The active group showed a small significant beneficial effect at week four. The overall results of the trial also demonstrated a significant improvement in ulcer size over the duration of the trial period in both active and placebo groups.
AuthorsS A LeVasseur, R D Helme
JournalJournal of advanced nursing (J Adv Nurs) Vol. 16 Issue 8 Pg. 952-6 (Aug 1991) ISSN: 0309-2402 [Print] England
PMID1779084 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Drug Combinations
  • F 14001
  • Placebos
  • Plant Extracts
  • Cetomacrogol
Topics
  • Administration, Topical
  • Aged
  • Aged, 80 and over
  • Cetomacrogol (administration & dosage, therapeutic use)
  • Double-Blind Method
  • Drug Combinations
  • Female
  • Hordeum
  • Humans
  • Male
  • Nursing Assessment
  • Placebos
  • Plant Extracts (administration & dosage, pharmacology, therapeutic use)
  • Pressure Ulcer (drug therapy, epidemiology, nursing)
  • Risk Factors
  • Wound Healing (drug effects)

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