Prevalence and predictors of maternal peripheral malaria parasitemia in central Mozambique.

Abstract

Malaria infection during pregnancy (MiP) is heterogeneously distributed even in malaria-endemic countries. Program planners require data to facilitate identification of highest-priority populations for MiP control. Using data from two cross-sectional studies of 5,528 pregnant women in 8 neighboring sites in Mozambique, we described factors associated with maternal peripheral parasitemia by using logistic regression. Principal multivariate predictors of maternal peripheral parasitemia were gravidity (odds ratio [OR] = 2.29, 95% confidence interval [CI] = 1.60-3.26 for primigravidae and OR = 1.61, 95% CI = 1.29-2.01 for secundigravidae compared with gravidity > or = 3); age (OR = 0.96 per year, 95% CI = 0.94-0.99); study site (OR = 1.45, 95% CI = 1.34-1.56 to 5.32, 95% CI = 4.92-5.75) for comparison with the reference site; and no maternal education (OR = 1.38, 95% CI = 1.15-1.66) compared with any education. Other predictors (in subgroups) were bed net use (OR = 0.49, 95% CI = 0.48-0.50); preventive sulfadoxine-pyrimethamine doses (OR = 0.25, 95% CI = 0.24-0.25); and infection with human immunodeficiency virus (HIV) (OR = 1.49, 95% CI = 1.11-2.00). Programmatic priorities should respond to heterogeneous distribution of multiple risk factors, including prevalence of malaria and infection with HIV, and maternal socioeconomic status.

• Authors: Paula E Brentlinger, Pablo Montoya, Ana Judith Blanco Rojas, Maria Ana Chadreque Correia, Martinho Dgedge, Francisco Saúte, Kenneth Gimbel-Sherr, Mary Anne Mercer, Stephen Gloyd
• Journal: The American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 77 Issue 2 Pg. 228-34 (Aug 2007) ISSN: 0002-9637 [Print] United States
• PMID: 17690391 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Topics

• Adult
• Age Factors
• Animals
• Cross-Sectional Studies
• Female
• Gravidity
• Humans
• Malaria, Falciparum (blood, epidemiology, parasitology)
• Mozambique (epidemiology)
• Parasitemia (epidemiology, parasitology)
• Plasmodium falciparum (growth & development)
• Pregnancy
• Pregnancy Complications, Parasitic (blood, epidemiology, parasitology)
• Prevalence
• Rural Population
• Social Class
• Urban Population