Abstract | PURPOSE: MATERIALS AND METHODS: Eligible men were 50 to 75 years old with serum prostate specific antigen 2.5 ng/ml or greater and 10 ng/ml or less (ages 50 to 60 years), or 3.0 ng/ml or greater and 10 ng/ml or less (older than 60 years), and an International Prostate Symptom Score of less than 25 (or less than 20 if already on alpha-blocker therapy). Acute prostatitis was an exclusion criterion. The National Institutes of Health Chronic Prostatitis Symptom Index was used to assess prostatitis-like symptoms. Spearman rank correlations were used to assess the relationship between acute and chronic inflammation, and Chronic Prostatitis Symptom Index scores for the pain, urinary symptoms and quality of life domains as well as average pain, total score and prostatitis-like symptoms. RESULTS: Data were available on 5,597 patients. The distribution of inflammation status was similar for those with and without chronic prostatitis-like symptoms. Significant correlations were found between average chronic inflammation, and total Chronic Prostatitis Symptom Index score and subscores for urinary symptoms and quality of life but the magnitude of these correlations was small. CONCLUSIONS:
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Authors | J Curtis Nickel, Claus G Roehrborn, Michael P O'leary, David G Bostwick, Matthew C Somerville, Roger S Rittmaster |
Journal | The Journal of urology
(J Urol)
Vol. 178
Issue 3 Pt 1
Pg. 896-900; discussion 900-1
(Sep 2007)
ISSN: 0022-5347 [Print] United States |
PMID | 17632164
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Azasteroids
- Enzyme Inhibitors
- 3-Oxo-5-alpha-Steroid 4-Dehydrogenase
- Dutasteride
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Topics |
- 3-Oxo-5-alpha-Steroid 4-Dehydrogenase
(therapeutic use)
- Aged
- Azasteroids
(therapeutic use)
- Biopsy, Needle
- Chronic Disease
- Dutasteride
- Enzyme Inhibitors
(therapeutic use)
- Humans
- Inflammation
- Male
- Middle Aged
- Pelvic Pain
(complications)
- Prostate
(pathology)
- Prostatic Neoplasms
(prevention & control)
- Prostatitis
(complications, diagnosis, pathology)
- Randomized Controlled Trials as Topic
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