Abstract | OBJECTIVE: METHODS: RESULTS: Acute physiology and chronic health evaluation II (APACHE II) scores of MV group were significantly higher than those of non-MV group at different time points after admission (all P<0.01). There was significant correlation of APACHE II with each inflammatory mediator at each time point and the coefficients were similar. By analysis of covariance, NO and APACHE II score were negatively correlated, other indexes were positively correlated with APACHE II score. There were not significant variances in two groups on the 1 st hospital day (all P>0.05); but on the 7 th hospital day, the levels of ET-1, ACE and CEC were all increased, but NO decreased (all P<0.05). NO content and APACHE II score could forecast the prognosis with the conclusion of Logistic analysis. CONCLUSION: There are very high correlations between the degree of vascular endothelial dysfunction and the seriousness of diseases in patients with SIRS. MV exerts significant damage to the vascular endothelial function in patients.
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Authors | Shuo Wang, Yi-xian Li, Chun-sheng Li |
Journal | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
(Zhongguo Wei Zhong Bing Ji Jiu Yi Xue)
Vol. 19
Issue 3
Pg. 168-71
(Mar 2007)
ISSN: 1003-0603 [Print] China |
PMID | 17376273
(Publication Type: English Abstract, Journal Article)
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Topics |
- Endothelium, Vascular
(physiopathology)
- Humans
- Respiration, Artificial
- Systemic Inflammatory Response Syndrome
(physiopathology, therapy)
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