[Polycystic ovary syndrome: an example of obesity-related cardiovascular complication affecting young women].

Abstract

Polycystic ovary syndrome (PCOS) is a good example of obesity-related cardiovascular complication affecting young women. PCOS is not only considered a reproductive problem but rather represents a complex endocrine, multifaceted syndrome with important health implications. Several evidences suggest an increased cardiovascular risk of cardiovascular disease associated with this syndrome, characterized by an impairment of heart structure and function, endothelial dysfunction and lipid abnormalities. All these features, probably linked to insulin-resistance, are often present in obese PCOS patients. Cardiovascular abnormalities represent important long-term sequelae of PCOS that need further investigations.

• Authors: Francesco Orio, Teresa Cascella, Francesco Giallauria, Stefano Palomba, Anna De Lorenzo, Rosa Lucci, Elena Ambrosino, Gaetano Lombardi, Annamaria Colao, Carlo Vigorito
• Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace (Monaldi Arch Chest Dis) Vol. 66 Issue 1 Pg. 48-53 (Mar 2006) ISSN: 1122-0643 [Print] Italy
• Vernacular Title: La sindrome dell'ovaio policistico: un esempio di complicanza cardiovascolare correlata all'obesità che colpisce giovani donne.
• PMID: 17125045 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Biomarkers
• Endothelin-1
• Plasminogen Activator Inhibitor 1

Topics

• Biomarkers (blood)
• Cardiovascular Diseases (blood, etiology, physiopathology)
• Endothelin-1 (blood)
• Female
• Humans
• Hypertrophy, Left Ventricular (etiology)
• Insulin Resistance
• Obesity (blood, complications, physiopathology)
• Plasminogen Activator Inhibitor 1 (blood)
• Polycystic Ovary Syndrome (blood, complications, physiopathology)
• Risk Assessment
• Risk Factors