Abstract | OBJECTIVES: METHODS: Patients 3 months to 18 years of age with acute pyelonephritis, with or without VUR, were assigned randomly to receive urinary antibiotic prophylaxis or not. Patients were monitored every 3 months for 1 year. Dimercaptosuccinic acid renal scans were repeated at 6 months or if there was a recurrence of febrile UTI. Urinalysis and urine culture were performed at each clinic visit. Renal ultrasound scans and voiding cystourethrograms were repeated at the end of 1 year of follow-up monitoring. RESULTS: Of the 236 patients enrolled in the study, 218 completed the 1-year follow-up monitoring. Groups were similar with respect to age, gender, and reflux grade distribution for those with VUR. No statistically significant differences were found among the groups with respect to rate of recurrent UTI, type of recurrence, rate of subsequent pyelonephritis, and development of renal parenchymal scars. CONCLUSIONS:
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Authors | Eduardo H Garin, Fernando Olavarria, Victor Garcia Nieto, Blanca Valenciano, Alfonso Campos, Linda Young |
Journal | Pediatrics
(Pediatrics)
Vol. 117
Issue 3
Pg. 626-32
(Mar 2006)
ISSN: 1098-4275 [Electronic] United States |
PMID | 16510640
(Publication Type: Journal Article, Multicenter Study, Randomized Controlled Trial)
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Topics |
- Acute Disease
- Adolescent
- Antibiotic Prophylaxis
- Child
- Child, Preschool
- Cicatrix
(etiology)
- Female
- Humans
- Infant
- Kidney
(diagnostic imaging, pathology)
- Male
- Pyelonephritis
(diagnostic imaging, etiology, prevention & control)
- Radionuclide Imaging
- Recurrence
- Treatment Outcome
- Vesico-Ureteral Reflux
(complications, diagnostic imaging)
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