Succimer (Dimercaptosuccinic Acid)

848  relevant articles (69 outcomes, 133 trials/studies) found for this Drug

Dimercaptosuccinic Acid; DMSA; 2,3 Dimercaptosuccinic Acid; Chemet; 2,3-Dimercaptosuccinic Acid; Ro-1-7977; SERB Brand of Succimer; Sanofi Brand of Succimer; Succicaptal; Succimer Antimony Sodium Salt, (R*,S*)-Isomer; Succimer, (R*,R*)-(+,-)-Isomer; Succimer, Dipotassium Salt; Succimer, Disodium Salt; Succimer, Monosodium Salt; Succimer, Rhenium Salt; Succimer, Tin Salt; Tin Dimercaptosuccinate; meso-Dimercaptosuccinic Acid; Dimercaptosuccinate, Tin; Dipotassium Salt Succimer; Disodium Salt Succimer; Monosodium Salt Succimer; Rhenium Salt Succimer; Ro 1 7977; Ro17977; Tin Salt Succimer; meso Dimercaptosuccinic Acid; Butanedioic acid, 2,3-dimercapto-, (R*,S*)-

Relationship Network

Drug Context: Research Results

Experts

1.	Tsiouris, Spyridon: 4 articles (12/2007 - 07/2004)
2.	Flora, S J S: 4 articles (11/2007 - 01/2003)
3.	Papantoniou, Vassilios: 3 articles (12/2007 - 01/2005)
4.	Sotiropoulou, Maria: 3 articles (06/2005 - 07/2004)
5.	Koutsikos, John: 3 articles (06/2005 - 07/2004)
6.	Kao, Chia-Hung: 3 articles (11/2002 - 06/2002)
7.	Pirmettis, Ioannis: 2 articles (12/2007 - 01/2005)
8.	Hansson, Sverker: 2 articles (12/2007 - 08/2007)
9.	Sixt, Rune: 2 articles (12/2007 - 08/2007)
10.	Stokland, Eira: 2 articles (12/2007 - 08/2007)

Related Diseases

1.	Poisoning 08/01/1990 - "meso-2,3-Dimercaptosuccinic acid (DMSA) is orally effective for the treatment of chronic lead intoxication in humans. " 12/09/1978 - "2,3-Dimercaptosuccinic acid (D.M.S.), a new orally effective agent for the treatment of heavy-metal intoxication, was administered to five lead-poisoned smelter workers for six days at dosages ranging from 8.4--12.7 mg/kg/day on the first day to 28.1--42.2 mg/kg/day on the last day. " 11/01/1978 - "The data indicate that DMSA might be effective in protecting the developing organism against morphological and/or behavioral teratological consequences of methylmercury poisoning in utero." 04/01/2000 - "Succimer is considered to be a safe and effective treatment for lead (Pb) poisoning, since it reduces body Pb levels without an apparent diuresis of other essential elements. " 10/01/1995 - "Short-term efficacy of oral dimercaptosuccinic acid in children with low to moderate lead intoxication." Order ALL the reference details at left...
2.	Cicatrix (Scar) 05/01/2009 - "DMSA scintigraphy was regarded as the gold standard for the diagnosis of renal scarring. " 08/01/2007 - "Accuracy of ultrasonic detection of renal scarring in different centres using DMSA as the gold standard." 02/01/2004 - "Ultrasonography in the evaluation of renal scarring using DMSA scan as the gold standard." 04/01/1999 - "The sensitivity of US for scarring, using DMSA as a gold standard, ranged from 37% to 100%, and its specificity from 65% to 99%. " 03/01/1992 - "The validity of DMSA as a cortical imaging agent is evaluated and the histological evidence for its efficacy derived from the animal model is reviewed, lending weight to its establishment as the "gold standard" for renal cortical scarring." Order ALL the reference details at left...
3.	Lead Poisoning (Poisoning, Lead) 02/01/1996 - "OBJECTIVE--To determine whether succimer (meso-2,3-dimercaptosuccinic acid) would be effective in reducing blood lead concentration in dogs with naturally acquired lead poisoning and whether treated dogs would develop clinically important adverse effects. " 08/01/1994 - "Renal clearance of total DMSA was greater in healthy adults (77.0 +/- 13.2 ml/min per square meter) than in either adults (24.7 +/- 3.3 ml/min per square meter) or children with lead poisoning (16.6 ml/min per square meter); renal clearance of the metabolites of DMSA was also greater in healthy adults (64.6 +/- 10.1 ml/min per square meter) than in either adults (35.4 +/- 8.4 ml/min per square meter) or children with lead poisoning (19.5 ml/min per square meter). " 01/01/1992 - "We conclude that a 5-day oral course of DMSA is effective in the treatment of children with severe lead poisoning. " 06/01/1998 - "The aim of this study was to evaluate the efficacy of meso-2,3-dimercaptosuccinic acid (DMSA) treatment in workers with increased lead absorption and no overt symptoms of lead poisoning. " 02/01/1996 - "CLINICAL IMPLICATIONS--In dogs with naturally acquired lead poisoning, succimer administered orally for 10 days effectively reduced blood lead concentrations and eliminated clinical signs of lead poisoning." Order ALL the reference details at left...
4.	Vesico-Ureteral Reflux (Vesicoureteral Reflux) 01/01/2009 - "In these studies, vesico-ureteral reflux was diagnosed by voiding cystourethrogram and kidney damage was assessed by either DMSA scan or urography. " 06/01/2004 - "The objective of this study was to evaluate the usefulness of DMSA scintigraphy performed during UTI as a predictor of patient outcome, to identify children at risk of events [vesico-ureteral reflux (VUR) or recurrent UTI] that may lead to the development of progressive renal damage. " 11/01/2003 - "MATERIALS AND METHODS: The study included 43 children investigated by DMSA and IVU, who had vesicoureteral reflux diagnosed and classified through voiding cystourethrography. " 09/01/1998 - "Five-year study of medical or surgical treatment in children with severe vesico-ureteral reflux dimercaptosuccinic acid findings. " 09/01/2009 - "There were significantly more infants with abnormal micturating voiding cystourethrograms (MCUGs) (P = 0.007), more refluxing ureters (P < 0.001) and more significant vesico-ureteral reflux (VUR) (>/= grade III) (P = 0.013) in the atypical group than in the typical group; while there was no significant difference in ultrasound (US) and DMSA scan findings between the two groups. " Order ALL the reference details at left...
5.	Arsenic Poisoning 01/01/2005 - "DMSA could be a safe and effective method for treating lead or arsenic poisoning, but one of the major disadvantages of chelation with DMSA has been its inability to remove lead from the intracellular sites because of its lipophobic nature. " 01/01/2003 - "The efficacy of monoisoamyl ester of dimercaptosuccinic acid in chronic experimental arsenic poisoning in mice." 05/01/2007 - "Slow recovery from severe inorganic arsenic poisoning despite treatment with DMSA (2.3-dimercaptosuccinic acid)." 09/16/2005 - "To address this problem, analogs of DMSA having lipophilic character, were examined against chronic arsenic poisoning in experimental animals. " 01/01/2001 - "Intentional overdose of dimercaptosuccinic acid in the course of treatment for arsenic poisoning." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Succimer (Dimercaptosuccinic Acid)
2.	Unithiol (DMPS)
3.	Arsenic
4.	Chelating Agents
5.	Technetium Tc 99m Dimercaptosuccinic Acid
6.	Pentetic Acid (DTPA)
7.	Edetic Acid (EDTA)
8.	Dimercaprol (B.A.L.)
9.	Calcium
10.	Thallium

Related Therapies and Procedures

1.	Lithotripsy (Extracorporeal Shockwave Lithotripsy)
2.	Chelation Therapy (Therapy, Chelation)
3.	Nephrectomy
4.	Intravenous Injections
5.	Drug Therapy (Chemotherapy)