Abstract | UNLABELLED: The preliminary outcomes of patients with acute liver failure treated with the Prometheus Fractionated Plasma Separation and Absorption (FPSA) system are presented herein. PATIENTS AND METHODS: The procedures were performed in 13 patients (4, intoxication by Amanita phalloides; 4, unknown reason; 3, acetaminophen intoxication; 1, Wilson disease, and 1, liver insufficiency after hemihepatectomy owing to metastases of colon adenocarcinoma). The patients were qualified for the procedure according to the King's College Hospital criteria. The patients' general status was assessed on basic of GCS, UNOS, and the 4-grade encephalopathy classifications. The procedures were performed with the Prometheus 4008H Fresenius Medical Care unit. RESULTS: CONCLUSIONS: The Prometheus FPSA-System was an effective detoxication method for patients with acute liver failure. The system was useful as a symptomatic treatment before liver transplantation allowing a longer wait for a graft.
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Authors | A Skwarek, M Grodzicki, P Nyckowski, M Kotulski, K Zieniewicz, B Michalowicz, W Patkowski, I Grzelak, A Paczkowska, D Giercuszkiewicz, J Sańko-Resmer, L Paczek, M Krawczyk |
Journal | Transplantation proceedings
(Transplant Proc)
2006 Jan-Feb
Vol. 38
Issue 1
Pg. 209-11
ISSN: 0041-1345 [Print] United States |
PMID | 16504704
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Biomarkers
(blood)
- Equipment Design
- Extracorporeal Circulation
(instrumentation, methods)
- Humans
- Liver Failure, Acute
(blood, mortality, therapy)
- Liver Function Tests
- Liver Transplantation
(physiology)
- Liver, Artificial
- Sorption Detoxification
- Survival Analysis
- Tachycardia
(epidemiology)
- Treatment Outcome
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