HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Pneumonia in the elderly (geriatric) population.

AbstractPURPOSE OF REVIEW:
Review of recent studies (2003 and 2004) concerning pneumonia in the very old.
RECENT FINDINGS:
Hospitalisation for community-acquired pneumonia (CAP) in the elderly is associated with a high mortality and with a high rate of readmission within the following year. Functional status, altered mental status, number of comorbidities, aspiration pneumonia, renal failure, and nutritional status are all indicators of adverse prognosis. Although Streptococcus pneumoniae, Haemophilus influenzae, Enterobacteriacae, and Staphylococcus aureus are the most frequently identified causative microorganisms, viruses account for up to 26% of hospital admissions for CAP. Chlamydia pneumoniae is also implicated in CAP and in nursing-home-acquired pneumonia (NHAP), with recent reports of outbreaks in nursing homes. Aspiration pneumonia is frequent in the elderly and occurs with increased frequency in patients with nasogastric tubes or percutaneous enterogastric tubes. In severe aspiration pneumonia, 20% of organisms implicated are anaerobic and 80% aerobic, most of which are gram-negative Enterobacteriaceae. Poor oral hygiene increases subsequent risk of pneumonia: dental plaque may act as a reservoir for pathogenic organisms implicated in CAP or NHAP. Prevention of CAP and NHAP relies on the combined use of influenza and pneumococcal vaccination, which decreases hospital admissions and in-hospital mortality for CAP.
SUMMARY:
Recent studies stress the importance of aspiration as a frequent mechanism of CAP, provide new insights as to causative organisms in this setting, and underline the contribution of combined vaccination in reducing morbidity and mortality.
AuthorsJean-Paul Janssens
JournalCurrent opinion in pulmonary medicine (Curr Opin Pulm Med) Vol. 11 Issue 3 Pg. 226-30 (May 2005) ISSN: 1070-5287 [Print] United States
PMID15818184 (Publication Type: Journal Article, Review)
Topics
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Community-Acquired Infections (diagnosis, drug therapy, epidemiology)
  • Female
  • Geriatric Assessment
  • Humans
  • Male
  • Pneumonia (diagnosis, drug therapy, epidemiology)
  • Pneumonia, Aspiration (diagnosis, epidemiology, therapy)
  • Prognosis
  • Risk Assessment
  • Severity of Illness Index
  • Survival Rate
  • Switzerland (epidemiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: