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Human Influenza (Influenza)

An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.
Also Known As:
Influenza; Grippe; Flu, Human; Human Flu; Influenza, Human; Human Influenzas; Influenza in Human; Influenzas; Influenzas, Human; Influenza in Humans
Networked: 36431 relevant articles (2863 outcomes, 4822 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Infections
2. Pneumonia (Pneumonitis)
3. Virus Diseases (Viral Diseases)
4. COVID-19
5. Human Influenza (Influenza)

Experts

1. Centers for Disease Control and Prevention (CDC): 138 articles (06/2015 - 03/2000)
2. García-Sastre, Adolfo: 128 articles (01/2022 - 04/2002)
3. Fry, Alicia M: 123 articles (03/2022 - 12/2006)
4. Monto, Arnold S: 119 articles (11/2022 - 03/2002)
5. Kawaoka, Yoshihiro: 113 articles (12/2022 - 01/2002)
6. Zimmerman, Richard K: 112 articles (10/2022 - 10/2002)
7. Nowalk, Mary Patricia: 98 articles (03/2022 - 01/2003)
8. Hurt, Aeron C: 97 articles (11/2022 - 01/2003)
9. Palese, Peter: 93 articles (01/2022 - 04/2002)
10. Ross, Ted M: 92 articles (11/2022 - 02/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Human Influenza:
1. VaccinesIBA
12/28/2022 - "In a previous challenge study, a single intranasal dose of the investigational vaccine M2SR demonstrated protection against a highly drifted H3N2 influenza challenge virus in a subset of vaccine recipients with a signature immune response. "
01/01/2019 - "Even though the in vivo efficacy of IY7640 did not reach complete protection in a lethal challenge study in mice, these results suggest that IY7640 has potential to be developed as a new type of anti-influenza drug.IMPORTANCE Anti-influenza drugs with broad-spectrum efficacy against antigenically diverse influenza viruses can be highly useful when no vaccines are available. "
01/02/2015 - "To the best of our knowledge, this study is the first report describing the immunological profile of the NP-containing VLPs vaccines in mice and chicken models, and the results demonstrate that the non-infectious, genome less VLPs, particularly those containing NP, represent a promising strategy for the development of a safe and effective vaccine to control pandemic influenza."
01/01/2014 - "In the present study, the immunogenicity and protection against a highly pathogenic H5N1 influenza challenge were evaluated after vaccination with an enterotropic NDV vector expressing an H5 haemagglutinin (rNDV-H5) in 1-day-old specific pathogen free chickens inoculated once, twice or once followed by a heterologous boost with an inactivated H5N9 vaccine (iH5N9). "
12/29/2001 - "A 2 year, multicentre, double-blind, placebo-controlled efficacy field trial of CAIV-T in children aged 15-71 months with annual re-immunization revealed the vaccine to be highly protective against culture-confirmed influenza. "
2. Influenza Vaccines (Influenza Vaccine)FDA Link
3. Antiviral Agents (Antivirals)IBA
4. Oseltamivir (Tamiflu)FDA Link
5. Neuraminidase (Sialidase)IBA
6. Hemagglutinins (Hemagglutinin)IBA
7. AntigensIBA
8. Zanamivir (Relenza)FDA Link
9. AntibodiesIBA
10. Proteins (Proteins, Gene)FDA Link

Therapies and Procedures

1. Therapeutics
2. Chemoprevention
3. Home Nursing (Nursing, Home)
4. Drug Therapy (Chemotherapy)
5. Intranasal Administration