Total mandibular reconstruction for massive osteolysis of the mandible (Gorham-Stout syndrome).

Abstract

Massive osteolysis (Gorham-Stout syndrome) is a rare condition of unknown aetiology that is thought to result from a localised endothelial proliferation of lymphatic vessels resulting in destruction and absorption of bone. The diagnosis of Gorham-Stout syndrome can be made only after first excluding osteolysis from infection, inflammation, endocrine disease, and cancer. The syndrome is rarely seen in the facial skeleton and has a variable prognosis. Many treatments have been advocated but only surgery and radiotherapy have had some success. We present a case of massive osteolysis of the entire mandible, which was reconstructed with a free vascularised fibular graft and bilateral prosthetic replacements of the temporomandibular (TMJ) joints. Four years later the fibular graft had been absorbed requiring further reconstruction with another fibula graft.

• Authors: M D Paley, C J Lloyd, C N Penfold
• Journal: The British journal of oral & maxillofacial surgery (Br J Oral Maxillofac Surg) Vol. 43 Issue 2 Pg. 166-8 (Apr 2005) ISSN: 0266-4356 [Print] Scotland
• PMID: 15749219 (Publication Type: Case Reports, Journal Article)

Topics

• Bone Transplantation (methods)
• Female
• Fibula (transplantation)
• Humans
• Joint Prosthesis
• Mandible (surgery)
• Mandibular Diseases (surgery)
• Middle Aged
• Oral Surgical Procedures
• Osteolysis, Essential (surgery)
• Recurrence
• Reoperation
• Syndrome
• Temporomandibular Joint (surgery)