Comparison of Campylobacter jejuni isolates implicated in Guillain-Barré syndrome and strains that cause enteritis by a DNA microarray.

Abstract

We asked whether Campylobacter jejuni isolated from patients with Guillain-Barré syndrome (GBS) differ from isolates isolated from patients with uncomplicated gastrointestinal infection using DNA microarray analysis. We found that specific GBS genes or regions were not identified, and microarray analysis confirmed significant genomic heterogeneity among the isolates.

• Authors: Edward E Leonard 2nd, Lucy S Tompkins, Stanley Falkow, Irving Nachamkin
• Journal: Infection and immunity (Infect Immun) Vol. 72 Issue 2 Pg. 1199-203 (Feb 2004) ISSN: 0019-9567 [Print] United States
• PMID: 14742576 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Topics

• Campylobacter jejuni (genetics)
• Enteritis (microbiology)
• Genetic Variation
• Genome, Bacterial
• Guillain-Barre Syndrome (microbiology)
• Humans
• Oligonucleotide Array Sequence Analysis (methods)