Abstract | BACKGROUND: CASE:
DHEA 200 mg/d was tested in chronic active pouchitis in a 35-year-old female patient. DHEA was given for eight weeks, and follow up for further eight weeks was performed. The number of stools dropped from 15-18/d to 8/d, the addition of mucus, which was observed initially, was absent during treatment. The consistence of stools improved from liquid/soft to soft/solid. Abdominal pain resolved and endoscopical signs of inflammation improved. Eight weeks after termination of treatment with DHEA, the patient again suffered from 12 to 18 soft to liquid stools per day and mild abdominal pain. CONCLUSION:
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Authors | F H Klebl, N Bregenzer, G Rogler, R H Straub, J Schölmerich, T Andus |
Journal | Zeitschrift fur Gastroenterologie
(Z Gastroenterol)
Vol. 41
Issue 11
Pg. 1087-90
(Nov 2003)
ISSN: 0044-2771 [Print] Germany |
PMID | 14648378
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Adjuvants, Immunologic
- Dehydroepiandrosterone
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Topics |
- Adjuvants, Immunologic
(administration & dosage, therapeutic use)
- Adult
- Colitis, Ulcerative
(surgery)
- Dehydroepiandrosterone
(administration & dosage, therapeutic use)
- Endoscopy
- Female
- Follow-Up Studies
- Humans
- Pouchitis
(diagnosis, drug therapy)
- Time Factors
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