Time course of pulmonary function before admission into ICU. A two-year retrospective study of COLD patients with hypercapnia.

Abstract

Changes in cardiopulmonary function were retrospectively evaluated back to two years before acute exacerbations requiring ICU admission in 16 COLD patients with chronic hypercapnic respiratory insufficiency (age: 61 +/- 6 years, group A). Fifteen hypercapnic COLD patients matched for age, sex, lung function, and blood gas values not requiring an ICU admission in a period of two years, served as control subjects (age: 66 +/- 7, group B). Periodic assessments of spirometry, arterial blood gas values, echocardiography, body weight, and red blood cell count performed in stable state were compared for differences between groups and changes over a period of two years. The results indicated that basal body weight, rate of deterioration over time in FEV1, VC, blood gas values, bicarbonates, and RVD may be related to the necessity of ICU admission in COLD patients with hypercapnic respiratory insufficiency.

• Authors: M Vitacca, K Foglio, S Scalvini, S Marangoni, A Quadri, N Ambrosino
• Journal: Chest (Chest) Vol. 102 Issue 6 Pg. 1737-41 (Dec 1992) ISSN: 0012-3692 [Print] United States
• PMID: 1446481 (Publication Type: Journal Article)

Chemical References

• Bronchodilator Agents
• Carbon Dioxide
• Oxygen

Topics

• Aged
• Bronchodilator Agents (therapeutic use)
• Carbon Dioxide (blood)
• Case-Control Studies
• Female
• Follow-Up Studies
• Forced Expiratory Volume (physiology)
• Glasgow Coma Scale
• Humans
• Hypercapnia (physiopathology)
• Intensive Care Units
• Lung (physiopathology)
• Lung Diseases, Obstructive (physiopathology)
• Male
• Middle Aged
• Oxygen (blood)
• Patient Admission
• Respiratory Insufficiency (physiopathology)
• Retrospective Studies
• Time Factors
• Vital Capacity (physiology)