HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Bicarbonates (Hydrogen Carbonate)

Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
Also Known As:
Hydrogen Carbonate; Bicarbonate Ion; Carbonic Acid Ions; Carbonate, Hydrogen; Carbonates, Hydrogen; Ion, Bicarbonate; Ions, Bicarbonate; Ions, Carbonic Acid; Bicarbonate; Bicarbonate Ions; Hydrogen Carbonates
Networked: 4983 relevant articles (186 outcomes, 418 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Supuran, Claudiu T: 16 articles (12/2022 - 11/2002)
2. Bushinsky, David A: 14 articles (01/2022 - 11/2002)
3. Bellomo, Rinaldo: 13 articles (12/2021 - 08/2002)
4. Wesson, Donald E: 12 articles (01/2022 - 08/2010)
5. Abramowitz, Matthew K: 12 articles (11/2021 - 07/2011)
6. Kalantar-Zadeh, Kamyar: 12 articles (01/2021 - 11/2004)
7. Raphael, Kalani L: 10 articles (01/2020 - 02/2011)
8. Kovesdy, Csaba P: 9 articles (01/2021 - 05/2007)
9. Madias, Nicolaos E: 8 articles (07/2021 - 01/2003)
10. Hostetter, Thomas H: 8 articles (01/2020 - 08/2009)

Related Diseases

1. Acidosis
2. Neoplasms (Cancer)
3. Dehydration (Water Stress)
4. Alkalosis
5. Pain (Aches)
04/01/2006 - "Bicarbonate buffered local anaesthetic solutions are known to reduce the pain of infiltration. "
07/01/1998 - "Bicarbonate buffering of local anaesthetics is known to significantly decrease the pain of their administration and yet few practising surgeons do so. "
11/01/1966 - "1. The changes in venous blood pH, p(CO2) and standard bicarbonate caused by tiring the forearm by (a) rhythmic work with free circulation, (b) rhythmic work with ischaemic circulation, were determined using the Astrup apparatus.2. For rhythmic work, opening and shutting the hand as quickly as possible for 2 min, the averaged results on six subjects were: pH fell 0.19 units; p(CO2) (after full oxygenation of venous blood) rose 52 mm Hg; standard bicarbonate fell 2.9 m-equiv/l.3. For rhythmic work during ischaemia and accompanied by pain, the averaged results on six subjects were: pH fell 0.19 units; p(CO2) (after full oxygenation of venous blood) rose 26 mm Hg; standard bicarbonate fell 6.3 m-equiv/l.4. These results are compared with those obtained in an earlier investigation on the effect of strong hand grips for 1 min."
01/01/2014 - "The majority of patients recovered with hydration, bicarbonate therapy, and pain medication. "
09/01/2017 - "Moderator analyses found (1) among patients with preprocedural pain, those in the bicarbonate group experienced less intradermal injection pain (0.85 ± 1.23) than patients in the control group (2.50 ± 2.09); (2) among patients with fatty or scattered fibroglandular tissue, those in the bicarbonate group (1.35 ± 1.95) experienced less intraparenchymal injection pain than the control group (3.52 ± 3.13); and (3) during ultrasound-guided biopsies, patients in the bicarbonate group experienced less tissue-sampling pain (0.23 ± 0.63) than the control group (1.79 ± 3.05). "

Related Drugs and Biologics

1. Lactic Acid (Lactate)
2. Acids
3. Solutions
4. Potassium
5. Sodium
6. Dialysis Solutions
7. Glucose (Dextrose)
8. Insulin (Novolin)
9. Calcium
10. Acetates (Acetic Acid Esters)

Related Therapies and Procedures

1. Therapeutics
2. Renal Dialysis (Hemodialysis)
3. Fluid Therapy (Oral Rehydration Therapy)
4. Peritoneal Dialysis
5. Resuscitation