Abstract | BACKGROUND: MATERIALS AND METHODS: From January 1999 to December 2000, we analysed, retrospectively, our data about single-agent VNR as a first-line chemotherapy in elderly pts (> or = 70 years) with ABC. Twenty-four pts were analysed. VNR was administered at the dose of 30 mg/m2, i.v., days 1 and 8, every 3 weeks for a maximum of 6 cycles. RESULTS: CONCLUSION: These results suggest that single agent VNR is active and well-tolerated in elderly pts with ABC. Further prospective trials are warranted.
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Authors | Antonio Rossi, Cesare Gridelli, Vittorio Gebbia, Gerardo Rosati, Anna Tortoriello, Paolo Maione, Nicola Borsellino, Nestore Rossi, Agata Pisano, Giuseppe Colantuoni, Rosario Vincenzo Iaffaioli, Vincenzo Castaldo, Luigi Manzione |
Journal | Anticancer research
(Anticancer Res)
2003 Mar-Apr
Vol. 23
Issue 2C
Pg. 1657-64
ISSN: 0250-7005 [Print] Greece |
PMID | 12820437
(Publication Type: Journal Article, Review)
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Chemical References |
- Antineoplastic Agents, Phytogenic
- Vinblastine
- Vinorelbine
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Topics |
- Aged
- Aged, 80 and over
- Antineoplastic Agents, Phytogenic
(adverse effects, therapeutic use)
- Breast Neoplasms
(drug therapy)
- Female
- Humans
- Retrospective Studies
- Vinblastine
(adverse effects, analogs & derivatives, therapeutic use)
- Vinorelbine
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