HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Seroprevalence survey of measles, rubella, varicella, and mumps antibodies in health care workers and evaluation of a vaccination program in a tertiary care hospital in Japan.

Abstract
Vaccine-preventable viral infections in health care workers (HCWs) have been on the rise for the past 10 years in Japan. To reduce the viral infections and the burden of exposure follow-up surveys at a tertiary care hospital in Osaka, Japan, a seroprevalence survey was conducted, and free vaccinations for measles, rubella, varicella, and mumps were offered to newly hired HCWs (199 physicians and 72 nurses and nursing assistants) who had negative serologic results for antibodies against these viruses. Negative antibody titers were obtained from 7.4% of the newly hired HCWs for measles, 12.5% for rubella, 4.1% for varicella, and 15.9% for mumps. The vaccination program for HCWs improved the vaccine-preventable infection rates and resulted in fewer exposure follow-up surveys, fewer lost work days, and fewer HCWs requiring hospitalization for these viral infections compared with those counted for the previous year. These data indicate that all HCWs should be strongly recommended to be vaccinated against (or have documented immunity to) these viruses in Japan, as is the case in the United States.
AuthorsSeishi Asari, Matsuo Deguchi, Kazuko Tahara, Masako Taniike, Masahiro Toyokawa, Isao Nishi, Mikio Watanabe, Yoshinori Iwatani, Kiyoko Makimoto
JournalAmerican journal of infection control (Am J Infect Control) Vol. 31 Issue 3 Pg. 157-62 (May 2003) ISSN: 0196-6553 [Print] United States
PMID12734521 (Publication Type: Journal Article)
Chemical References
  • Antibodies, Viral
  • Chickenpox Vaccine
  • Measles Vaccine
  • Mumps Vaccine
  • Rubella Vaccine
Topics
  • Adult
  • Antibodies, Viral (blood)
  • Chi-Square Distribution
  • Chickenpox (epidemiology, prevention & control)
  • Chickenpox Vaccine (administration & dosage)
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Health Personnel
  • Humans
  • Infection Control (methods)
  • Japan (epidemiology)
  • Male
  • Measles (epidemiology, prevention & control)
  • Measles Vaccine (administration & dosage)
  • Middle Aged
  • Mumps (epidemiology, prevention & control)
  • Mumps Vaccine (administration & dosage)
  • Rubella (epidemiology, prevention & control)
  • Rubella Vaccine (administration & dosage)
  • Seroepidemiologic Studies

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: