The purpose of this study was to evaluate the effects of laparoscopic surgery on the symptoms associated with ovarian
endometrioma. We also examined serum
IL-6 concentrations in patients with
endometrioma. Ninety-two patients who underwent laparoscopic surgery for ovarian
endometrioma were enrolled in this study. The mean duration of follow-up was 27.6 months. Transvaginal ultrasound examinations revealed a recurrence of
endometrioma in 13% of the cases. We evaluated the severity of
dysmenorrhea using a 0-3-point verbal rating scale, and found that the
dysmenorrhea score was statistically improved after the operation. Follicular growth was preserved in 94%, and the pregnancy rate was 43%. We measured serum
IL-6 concentrations in 14 patients with ovarian
endometrioma and 4 patients with benign
gynecologic disease without
endometriosis.
IL-6 was significantly higher in patients with
endometrioma than in those without
endometriosis at the time of diagnosis. The mean serum
IL-6 concentration significantly decreased after the operation. In conclusion, laparoscopic surgery is effective for alleviating
pain and preserving fertility in patients with
endometrioma. Measurements of serum
IL-6 concentrations may be useful for the management of
endometrioma.