| Abstract | To assess the long-term follow-up of the globus pallidus internus (GPi) stimulation, six patients were evaluated every year by using the Unified Parkinson's Disease Rating Scale (UPDRS). Three years postoperatively, GPi stimulation led to a significant improvement of dyskinesia severity (50%, P = 0.05) and activities of daily living (subscore of quality of life scale, 9%, P = 0.05). However, the improvement induced by chronic pallidal stimulation on the mean daily duration in the off state was lost at the last assessment. |
| Authors | Franck Durif, Jean-Jacques Lemaire, Bérengère Debilly, Gérard Dordain
(Affiliation: Fédération de Neurologie, Hôpital Gabriel Montpied, Clermont Ferrand, France. fdurif at chu-clermontferrand.fr)
|
| Journal | Movement disorders : official journal of the Movement Disorder Society
(Mov Disord)
Vol. 17
Issue 4
Pg. 803-7
(Jul 2002)
ISSN: 0885-3185 United States |
| PMID | 12210880
(Publication Type: Journal Article)
|
| Copyright | Copyright 2002 Movement Disorder Society |
| Chemical References |
- Antiparkinson Agents
- Levodopa
|
| Topics |
- Activities of Daily Living
(classification)
- Aged
- Antiparkinson Agents
(administration & dosage)
- Combined Modality Therapy
- Dominance, Cerebral
(physiology)
- Electric Stimulation Therapy
- Electrodes, Implanted
- Female
- Follow-Up Studies
- Globus Pallidus
(physiopathology)
- Humans
- Levodopa
(administration & dosage)
- Male
- Middle Aged
- Motor Skills
(physiology)
- Parkinson Disease
(diagnosis, physiopathology, therapy)
- Quality of Life
|
