Abstract | BACKGROUND AND STUDY AIMS: PATIENTS AND METHODS: Records of 2826 patients who had undergone endoscopic retrograde cholangiopancreatography between 1995 and 1999 were reviewed for the presence of choledochocele and/or periampullary carcinoma. As an evidence of pancreaticobiliary reflux, amylase activity was examined in common duct bile obtained at surgery or by endoscopy. The prevalence of periampullary carcinoma was compared between patients with and without choledochocele. RESULTS: A total of 11 patients were diagnosed as having a choledochocele. The amylase level in bile was higher in patients with choledochocele (120,922 +/- 62,269 IU/l; n = 4) than in previously examined patients with functioning gallbladders (15 +/- 24 IU/l; n = 10, P = 0.005). The prevalence of periampullary carcinoma in patients with choledochocele (27%, 3/11) was significantly higher than that in those without choledochocele (0.9%, 26/2815; P<0.0002). CONCLUSION:
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Authors | T Ohtsuka, K Inoue, J Ohuchida, T Nabae, S Takahata, H Niiyama, K Yokohata, Y Ogawa, K Yamaguchi, K Chijiiwa, M Tanaka |
Journal | Endoscopy
(Endoscopy)
Vol. 33
Issue 7
Pg. 614-9
(Jul 2001)
ISSN: 0013-726X [Print] Germany |
PMID | 11473335
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Aged
- Aged, 80 and over
- Amylases
(analysis)
- Bile
(enzymology)
- Cholangiopancreatography, Endoscopic Retrograde
- Choledochal Cyst
(complications, diagnosis, enzymology)
- Common Bile Duct
(pathology)
- Common Bile Duct Neoplasms
(etiology)
- Dilatation, Pathologic
- Female
- Humans
- Male
- Middle Aged
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