Abstract | AIMS: METHODS: RESULTS: CONCLUSIONS:
Telomerase activation occurs in hydatidiform mole with a similar incidence to early normal placentas. This supports the concept that hydatidiform mole is essentially an abnormal conceptus. There is an association between telomerase activation and the development of persistent trophoblastic disease. Further study is warrant to confirm the prognostic significance of telomerase activity in hydatidiform mole.
|
Authors | A N Cheung, D K Zhang, Y Liu, H Y Ngan, D H Shen, S W Tsao |
Journal | Journal of clinical pathology
(J Clin Pathol)
Vol. 52
Issue 8
Pg. 588-92
(Aug 1999)
ISSN: 0021-9746 [Print] England |
PMID | 10645228
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Biomarkers, Tumor
- Telomerase
|
Topics |
- Biomarkers, Tumor
(metabolism)
- Choriocarcinoma
(enzymology)
- Female
- Humans
- Hydatidiform Mole
(enzymology)
- Placenta
(enzymology)
- Pregnancy
- Prognosis
- Telomerase
(metabolism)
- Tumor Cells, Cultured
- Uterine Neoplasms
(enzymology)
|