Cytoreduction Surgical Procedures

Operative procedures carried out to reduce a mass of tissue, for example, to reduce the total amount of tissue composing a tumor.

Also Known As:

Cytoreductive Surgery; Cytoreductive Surgical Procedures; Debulking Surgical Procedures; Cytoreduction Surgical Procedure; Cytoreductive Surgeries; Cytoreductive Surgical Procedure; Debulking Surgical Procedure; Procedure, Cytoreduction Surgical; Procedure, Cytoreductive Surgical; Procedure, Debulking Surgical; Surgery, Cytoreductive; Surgical Procedure, Cytoreduction; Surgical Procedure, Cytoreductive; Surgical Procedure, Debulking; Surgical Procedures, Cytoreductive

Networked: 4632 relevant articles (423 outcomes, 635 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 34913
- Cytoreduction Surgical Procedures: 4632

Experts

1.	Sugarbaker, Paul H: 111 articles (04/2022 - 02/2002)
2.	Morris, David L: 87 articles (06/2022 - 06/2007)
3.	Glehen, Olivier: 87 articles (04/2022 - 04/2004)
4.	Levine, Edward A: 75 articles (06/2022 - 01/2003)
5.	Deraco, Marcello: 66 articles (08/2022 - 01/2002)
6.	Shen, Perry: 59 articles (06/2022 - 01/2003)
7.	Baratti, Dario: 52 articles (08/2022 - 07/2003)
8.	Kusamura, Shigeki: 51 articles (01/2022 - 09/2002)
9.	Chua, Terence C: 49 articles (01/2019 - 02/2009)
10.	Liauw, Winston: 47 articles (06/2022 - 07/2009)

Related Diseases

1.	Peritoneal Neoplasms 08/01/2012 - "Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is the best treatment of several peritoneal surface malignancies. " 01/01/2021 - "Complete cytoreductive surgery with hyperthermic intraperitoneal chemotherapy is an effective treatment for improving prognosis of selected patients with peritoneal carcinomatosis. " 03/01/2019 - "Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) has been proven effective in select patients with peritoneal carcinomatosis (PC) from CRC, although it has not been evaluated specifically in patients < 50 years. " 11/01/2016 - "Complete cytoreductive surgery (CRS), combining organ resection and peritonectomy, is the only treatment that could offer cure for patients with peritoneal carcinomatosis. " 06/01/2015 - "Surgical procedures that combine both complete cytoreductive surgery (CCRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have improved the survival of patients with peritoneal carcinomatosis (PC). "
2.	Ovarian Neoplasms (Ovarian Cancer) 07/02/2023 - "Conclusions: A complete secondary cytoreductive surgery (SCS) in recurrent ovarian cancer (ROC) demonstrates an improvement in the OS and DFS, and this benefit is most evident in cases where complete cytoreductive surgery is achieved. " 01/01/2022 - "Despite the improvement in quality of cytoreductive surgery as well as development of novel drugs and chemotherapy regimens, still most women with ovarian cancer will ultimately develop recurrent disease and die of their disease. " 09/01/2001 - "Confirmation of the efficacy of cytoreductive surgery may cultivate a consensus about the most appropriate therapeutic objective and strategy for advanced ovarian cancer. " 07/01/1995 - "The best treatment results for advanced-stage ovarian cancer patients are obtained with cytoreductive surgery followed by combination chemotherapy. " 03/01/1994 - "It is undeniable that most patients with advanced ovarian cancer derive benefit from primary cytoreductive surgery, with relief of symptoms, prolonged survival, improved quality of life, and establishment of a definitive diagnosis. "
3.	Neoplasms (Cancer) 11/01/2021 - "Peritoneal Cancer Index (PCI) and complete cytoreduction are the best outcome predictors following cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). " 01/01/2008 - "The best results were reported in patients who had had cytoreductive surgery for primary tumor, radiofrequency ablation and chemotherapy (42). " 10/01/2005 - "Despite the ability of current chemotherapy and cytoreductive surgery to put patients in remission, most patients with advanced cancer will eventually relapse. " 08/01/2002 - "Currently, neoadjuvant chemotherapy is most beneficial for women who are medically impaired and unable to tolerate aggressive cytoreductive surgery and for women who are found to have such aggressive cancers that optimal cytoreductive surgery does not appear by diagnostic imaging or direct visualization to be possible." 12/16/2021 - "In the past decade, new treatments and multimodal strategies helped to improve patient survival and quality of life and the premise that peritoneal malignancies are fatal diseases has been dismissed as management strategies, including complete cytoreductive surgery embedded in perioperative systemic chemotherapy, can provide cure in selected patients. "
4.	Neoplasm Metastasis (Metastasis) 11/01/2022 - "Survival of patients affected by colorectal cancer peritoneal metastases (CRC-PM) can be improved with combined complete cytoreductive surgery (CCRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). " 11/01/2014 - "Complete cytoreductive surgery (CCRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) is on the verge of becoming the gold standard treatment for selected patients presenting peritoneal metastases (PM) of colorectal origin. " 08/28/2023 - "Is cytoreductive surgery and hyperthermic intraperitoneal chemotherapy still beneficial in patients diagnosed with colorectal peritoneal metastasis who underwent palliative chemotherapy?" 03/25/2021 - "In recent years, with the application and promotion of laparoscopic technology, neoadjuvant intraperitoneal and systemic chemotherapy, hyperthermic intraperitoneal chemotherapy and cytoreductive surgery, through perioperative comprehensive treatment strategies by multidisciplinary team, the quality of life and survival of patients with peritoneal metastasis have been significantly improved. " 10/01/2016 - "Cytoreductive surgery and hyperthermic chemoperfusion (HIPEC) are only beneficial in few patients with resectable peritoneal metastasis. "
5.	Ovarian Epithelial Carcinoma 07/01/2016 - "A thorough laparoscopic assessment of the abdominopelvic cavity is a crucial step in the workup of primary advanced epithelial ovarian cancer to decide whether up-front cytoreductive surgery or neoadjuvant chemotherapy is the best option for adequate management. " 11/01/2003 - "In a prospective randomized trial, consolidation treatment with radiotherapy or chemotherapy was compared with no treatment in a series of 172 patients with epithelial ovarian carcinoma, FIGO stage III, with complete surgical remission after primary cytoreductive surgery and induction chemotherapy. " 05/01/2003 - "In a prospective randomized trial, consolidation treatment with radiotherapy or chemotherapy was compared with no treatment in a series of 172 patients with epithelial ovarian carcinoma, FIGO stage III, with complete surgical remission after primary cytoreductive surgery and induction chemotherapy. " 01/01/2016 - "Included were 305 epithelial ovarian cancer patients who reached complete remission after cytoreductive surgery and first-line chemotherapy. " 07/01/2007 - "Twenty six patients received PET-CT imaging, who were all diagnosed as primary epithelial ovarian cancer of stage II - IV and had complete remission after cytoreductive surgery and multiple courses of chemotherapy in Shandong Provincial Cancer Hospital. "

Related Drugs and Biologics

1.	Platinum
2.	Paclitaxel (Taxol)
3.	Cisplatin (Platino)
4.	Carboplatin (JM8)
5.	Doxorubicin (Adriamycin)
6.	Bevacizumab (Avastin)
7.	Mitomycin (Mitomycin-C)
8.	Monoclonal Antibodies
9.	Biomarkers (Surrogate Marker)
10.	Proteins (Proteins, Gene)

Related Therapies and Procedures

1.	Hyperthermic Intraperitoneal Chemotherapy
2.	Drug Therapy (Chemotherapy)
3.	Therapeutics
4.	Neoadjuvant Therapy
5.	Combination Drug Therapy (Combination Chemotherapy)