Peroxisomal Multifunctional Protein-2
A dimeric protein found in liver peroxisomes that plays an important role in FATTY ACID metabolism and steroid metabolism. The dimer is formed by cleavage of a single protein precursor and contains an enoyl-CoA hydratase-2 domain and a second domain that displays (S)-3-hydroxyacyl-CoA dehydrogenase and 17-beta-estradiol dehydrogenase activities. The enzyme is stereospecific with regards to arrangement of the substrate double bonds and position of the 3-hydroxy group of the reaction intermediate. It is complemented by PEROXISOMAL BIFUNCTIONAL ENZYME, which has the opposite reaction stereospecificity.
Also Known As:
17-beta-Hydroxysteroid Dehydrogenase 4; 3-alpha,7-alpha,12-alpha-Trihydroxy-5-beta-Cholest-24-enoyl-CoA Hydratase; Peroxisomal Multifunctional Enzyme Type 2; 17 beta Hydroxysteroid Dehydrogenase 4; 4, 17-beta-Hydroxysteroid Dehydrogenase; Dehydrogenase 4, 17-beta-Hydroxysteroid; Multifunctional Protein-2, Peroxisomal; Peroxisomal Multifunctional Protein 2
Networked: 4
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
| 1. | Baes, Myriam:
4 articles
(01/2018 - 10/2013)
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| 2. | De Munter, Stephanie:
3 articles
(01/2018 - 10/2013)
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| 3. | Beckers, Lien:
2 articles
(01/2018 - 10/2013)
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| 4. | Brites, Pedro:
2 articles
(01/2018 - 10/2016)
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| 5. | Malheiro, Ana Rita:
2 articles
(01/2018 - 10/2016)
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| 6. | Verheijden, Simon:
2 articles
(10/2016 - 10/2013)
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| 7. | Bamps, Dorien:
1 article
(01/2018)
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| 8. | Bormans, Guy:
1 article
(01/2018)
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| 9. | Declercq, Lieven:
1 article
(01/2018)
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| 10. | Geric, Ivana:
1 article
(01/2018)
|
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