Vitamin B 6 Deficiency (Pyridoxine Deficiency)

Subscribe to Selected New Research on Vitamin B 6 Deficiency

475 relevant articles (14 outcomes, 33 trials/studies) found for this Disease

Description: A nutritional condition produced by a deficiency of VITAMIN B 6 in the diet, characterized by dermatitis, glossitis, cheilosis, and stomatitis. Marked deficiency causes irritability, weakness, depression, dizziness, peripheral neuropathy, and seizures. In infants and children typical manifestations are diarrhea, anemia, and seizures. Deficiency can be caused by certain medications, such as isoniazid.

Also Known As:

Pyridoxine Deficiency; Vitamin B6 Deficiency; Deficiency, Pyridoxine; Deficiency, Vitamin B 6; Deficiency, Vitamin B6; B6 Deficiencies, Vitamin; B6 Deficiency, Vitamin; Deficiencies, Vitamin B6; Vitamin B6 Deficiencies

Relationship Network

Disease Context: Research Results

Nutritional and Metabolic Diseases

Nutrition Disorders: 182

Malnutrition: 6748

Deficiency Diseases: 367

Avitaminosis: 692

Vitamin B Deficiency: 28

Vitamin B 6 Deficiency: 475

Related Diseases

1.	Carpal Tunnel Syndrome
2.	Chronic Kidney Failure (Chronic Renal Failure)
3.	Fibrosis (Cirrhosis)
4.	Dementia (Dementias)
5.	Celiac Disease (Celiac Sprue)

Experts

1.	Noguchi, Yoshimasa: 1 article (02/2008)
2.	Kuwahara, Hiroya: 1 article (02/2008)
3.	Mizusawa, Hidehiro: 1 article (02/2008)
4.	Inaba, Akira: 1 article (02/2008)
5.	Mashiyama, Susan T: 1 article (01/2008)
6.	Leklem, James E: 1 article (01/2008)
7.	Sarmiento, Stella: 1 article (01/2008)
8.	Ames, Bruce N: 1 article (01/2008)
9.	Roitman, Esther: 1 article (01/2008)
10.	Hansen, Christine M: 1 article (01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Vitamin B 6 Deficiency:

1.	Vitamin B 6IBA 01/01/1991 - "The present study indicates that vitamin B6 deficiency is prevalent in CDC stage III HIV-1-infected subjects, despite adequate dietary vitamin B6 intake" 11/01/1977 - "Two metabolic trials using early-weaned piglets were performed to find out whether highly vitamin B6 deficient prest,rter- or starter feeds (0.4 mg vitamin B6/Kg) would affect the excretion and retention of Ca, P, Mg, K and Na as compared with pair-fed control animals given 6.5 mg B6/Kg. The depleted animals showing typical vitamin B6 deficiency symptoms in the course of the trials, were found to excrete in the feces somewhat smaller amounts of minerals during both metabolic periods" 08/01/2007 - "Women with sufficient vitamin B6 had a higher adjusted hazard ratio of conception (HR=1.4, 95% CI: 1.1, 1.9) and a lower adjusted odds ratio of early pregnancy loss in conceptive cycles (odds ratio=0.7, 95% CI: 0.4, 1.1) than did women with vitamin B6 deficiency" 06/01/2007 - "Collectively, these data indicate that vitamin B(6) restriction decreases the activity and stability of SHMT, and that the cytoplasmic isozyme is more sensitive to vitamin B(6) deficiency than the mitochondrial isozyme in MCF-7 cells." 05/01/2002 - "Since vitamin B6 deficiency causes profound effects on immune system function, dietary or supplemented vitamin B6 intake is suggested for hospitalized patients." Order ALL the reference details at left...
2.	Pyridoxine (Pyridoxin)FDA Link 04/01/1999 - "The aim of this study was to investigate the effect of pyridoxine (Vitamin B6) deficiency on the immunological response of BALB/c mice infected with the parasite T" 05/01/1998 - "This study tested plasma pyridoxine (vitamin B6) deficiency status as a predictor of overall psychological distress and specific mood states in this model, controlling for HIV-1 serostatus" 11/01/1968 - "Studies on vitamin B6 deficiency during pregnacy and in various pathological states using pyridoxine saturation test]" 01/01/1998 - "OC-induced psychological disturbances were interpreted for years as evidence of pyridoxine (vitamin B6) deficiency" 04/01/1994 - "The increase in the activity of NDMA-demethylase induced by dietary pyridoxine deficiency can be reversed by supplementation of pyridoxine (500 micrograms), i.p., daily for two consecutive days" Order ALL the reference details at left...
3.	Glucose (Dextrose)FDA LinkGeneric 09/01/1983 - "Subclinical pyridoxine deficiency of the degree seen in this study is apparently associated with improved, rather than impaired, glucose tolerance." 09/01/1999 - "Vitamin B6 deficiency decreases the glucose utilization in cognitive brain structures of rats." 09/01/1983 - "Glucose tolerance in subclinical pyridoxine deficiency in man." 01/01/1983 - "It appears that severe depression and impairment of glucose tolerance are the only important abnormalities encountered in OC users related to vitamin B6 deficiency" 01/01/1982 - "Pyridoxine deficiency resulted in significantly lower levels of liver glucose than in pair-fed controls but no significant change in the serum glucose concentration" Order ALL the reference details at left...
4.	EnzymesIBA 01/01/1982 - "Vitamin B6 deficiency as related to oxalate-synthesizing enzymes in growing rats." 07/02/1979 - "The developmental profile of fatty acid elongation enzymes of rat brain microsomes and mitochondria and the consequences of pyridoxine deficiency have been investigated" 03/01/1967 - "Blood transaminase activities in vitamin B6 deficiency: effect of depletion and repletion on the erythrocyte enzymes." 11/01/1998 - "Although the activity of glutathione-dependent enzymes was significantly greater in deficient rats than in controls, this stimulation was only partially able to counteract the peroxidative damage due to vitamin B6 deficiency." 01/01/1990 - "Changes in kinetic properties of pyridoxal-dependent enzymes during dietary vitamin B6 deficiency in rats]" Order ALL the reference details at left...
5.	Methionine (L-Methionine)FDA Link 01/01/2002 - "Vitamin B6 deficiency may result in high tHcy levels, especially after a methionine load (PML)" 01/01/1976 - "Decarboxylation of S-adenosyl-L-methionine in vitamin B6 deficiency in rat liver." 01/01/1974 - "Methionine metabolism in pyridoxine deficiency." 01/01/1972 - "Methionine load test in pyridoxine deficiency." 07/01/1977 - "Attempts were therefore made to induce atherosclerosis in Macaca radiata, maintained on a high-protein, high-methionine and high-fat diet by inducing pyridoxine deficiency with deoxypyridoxine" Order ALL the reference details at left...
6.	xanthurenic acidIBA 07/01/1952 - "Detection of vitamin B6 deficiency; utilization of an improved method for rapid determination of xanthurenic acid in urine." 03/01/1996 - "Measurement of urinary xanthurenic acid (XA) has been used clinically to study a variety of disorders caused by vitamin B6 deficiency" 01/01/1975 - "3) Saturated fat increased urinary xanthurenic acid in vitamin B6 deficiency." 09/01/1959 - "The state of vitamin B6 deficiency as measured by urinary xanthurenic acid." 04/01/1957 - "Xanthurenic acid and N1-methylinicotinamide in pyridoxine deficiency due to diet or desoxypyridoxine.]" Order ALL the reference details at left...
7.	Tryptophan (L-Tryptophan)FDA Link 06/01/1992 - "In contrast to previous reports, this is different from the pattern of tryptophan metabolism seen in vitamin B6 deficiency" 05/08/1981 - "The etiology of this photodermatosis of child is unknown, but associated disturbances in tryptophan metabolism in some cases seem to be linked to a vitamin B6 deficiency." 11/01/1980 - "It is suggested that a raised hydroxykynurenine/hydroxyanthranilic acid ratio does not necessarily indicate vitamin B6 deficiency but may represent a nonspecific response of tryptophan metabolism to stress." 01/01/1977 - "These errors of tryptophan metabolism in PEM are suggested to be due to defects in the enzyme systems involved rather than to vitamin B6 deficiency." 10/01/1973 - "Tryptophan metabolic disorder in pyridoxine deficiency in children]" Order ALL the reference details at left...
8.	VitaminsIBA 01/01/1999 - "Maternal deficiencies in more than one vitamin further increased the risk of infant thiamin and pyridoxine deficiency" 02/01/1997 - "It was concluded that the requirements of the elderly for vitamins B1, B2 and C, and the biochemical deficiency threshold values used to indicate vitamin B6 deficiency, need review." 05/01/1990 - "The functional methods used for the vitamin assay (ACT activity of red blood cells and pyrodoxale-5-phosphate effect) have revealed significant vitamin B6 deficiency in 81.1% of the patients" 01/01/1990 - "Vitamin B6 deficiency was induced in mice by maintenance for 4 weeks on a vitamin B6-free diet" 01/01/1983 - "Vitamin B6 deficiency can be either exogenous (when intake falls below the recommended dietary allowance) or conditioned (in cases where the physiologic requirement for the vitamin is higher than the dietary allowance)" Order ALL the reference details at left...
9.	Thiamine (Aneurin)FDA Link 11/11/2001 - "Among patients with chronic alcoholic liver diseases the direct toxic effect of alcohol is of particular relevance, however, malabsorption, impairment of axoplasmatic transport, changes of intermedier metabolism as well as thiamine and pyridoxine deficiency are of importance as well" 07/01/1965 - "BLOOD TRANSAMINASE ACTIVITIES IN VITAMIN B6 DEFICIENCY: EFFECT OF CONCURRENT THIAMINE AND RIBOFLAVIN DEFICIENCIES." 12/01/1949 - "Nutritional concepts as revealed by studies of thiamine, folic acid and pyridoxine deficiency in the rhesus monkey." 09/01/1982 - "Thiamine, riboflavin and pyridoxine deficiency in psychiatric in-patients." 01/01/1948 - "The effect of thiamine and calcium supplements on the development of signs of pyridoxine deficiency." Order ALL the reference details at left...
10.	Taurine FDA Link 12/01/1974 - "VI. Vitamin B6 deficiency and taurine synthesis in the rat." 06/01/1971 - "Cystine metabolism in vitamin B 6 deficiency: evidence of multiple taurine pools." 09/01/1966 - "Effect of age, vitamin B6 deficiency, isoniazid and deoxypyridoxine on the urinary taurine of the rat." 11/01/1956 - "Influence of vitamin B6 deficiency on conjugated glycine and taurine content of the bile in rats.]" 04/01/1986 - "Vitamin B6 deficiency without estrogen treatment raised the levels of taurine in the blood of the animals treated with a L-methionine test-load" Order ALL the reference details at left...

Therapies and Procedures

1.	Contraception (Birth Control) 05/01/1986 - "In all three centres the majority of the study population suffered from biochemical riboflavin and/or pyridoxine deficiency even before initiating contraception" Order ALL the reference details at left...
2.	Renal Dialysis (Hemodialysis) 01/01/1991 - "Vitamin B6 deficiency on hemodialysis causing sideroblastic anemia." 05/01/1981 - "Vitamin B6 deficiency was evaluated in 37 patients with chronic renal failure and in 71 patients undergoing maintenance hemodialysis (HD) or intermittent peritoneal dialysis (PD)" 11/01/1997 - "For prevention of vitamin B6 deficiency in hemodialysis and CAPD patients we recommend the following doses of pyridoxine: for patients without EPO treatment 5 mg/day, and with EPO treatment 20 mg/day" 10/01/1989 - "Vitamin B6 deficiency in hemodialysis patients has been previously studied, but the need for daily pyridoxine supplementation in patients on chronic peritoneal dialysis (CPD) remains unclear" 04/01/2001 - "BACKGROUND/AIM: Pyridoxine deficiency may be the cause of failure to respond appropriately to iron and erythropoietin (EPO) administration in hemodialysis patients" Order ALL the reference details at left...
3.	Continuous Ambulatory Peritoneal Dialysis (CAPD) 10/01/1989 - "Therefore, we studied a group of 11 stable patients, nine on CAPD and two CCPD, to test for vitamin B6 deficiency and to establish daily requirements" 11/01/1997 - "For prevention of vitamin B6 deficiency in hemodialysis and CAPD patients we recommend the following doses of pyridoxine: for patients without EPO treatment 5 mg/day, and with EPO treatment 20 mg/day" 01/01/1992 - "According to our results the long-term daily oral supplementation of 6 mg vitamin B6 was sufficient for prevention of vitamin B6 deficiency in chronic renal failure, regular dialysis treatment and CAPD groups of patients" Order ALL the reference details at left...
4.	Peritoneal Dialysis 01/01/2000 - "Vitamin B6 deficiency in elderly patients on chronic peritoneal dialysis." 01/01/2000 - "When peripheral neuropathy is suspected in elderly patients on chronic peritoneal dialysis, vitamin B6 deficiency should be taken into consideration as the cause" 05/01/1981 - "Vitamin B6 deficiency was evaluated in 37 patients with chronic renal failure and in 71 patients undergoing maintenance hemodialysis (HD) or intermittent peritoneal dialysis (PD)" 10/01/1989 - "Vitamin B6 deficiency in hemodialysis patients has been previously studied, but the need for daily pyridoxine supplementation in patients on chronic peritoneal dialysis (CPD) remains unclear" Order ALL the reference details at left...
5.	Homologous Transplantation (Allograft) 07/01/1958 - "The favorable effect of pyridoxine deficiency on skin homograft survival." 01/01/1969 - "Effect of semicarbazide and pyridoxine deficiency on survival of canine renal homografts." Order ALL the reference details at left...

Best Treatments:
Research Summary Report
on Vitamin B 6 Deficiency

*WARNING* This specific disease subtype has a relatively small number of significant evidence outcomes. You may proceed to order anyway, or go back to the search field and enter a more general type of the target illness. Once your report has been ordered, however, we can't refund the purchase.

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 14 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>