|1.||Roberts, Jeanette C: 5 articles (02/2007 - 07/2003)|
|2.||Krauth-Siegel, R Luise: 4 articles (10/2008 - 02/2003)|
|3.||Franklin, Michael R: 4 articles (03/2007 - 01/2005)|
|4.||El-Sayed, Wael M: 4 articles (03/2007 - 06/2004)|
|5.||Fang, Jianguo: 3 articles (01/2015 - 04/2006)|
|6.||Hatfield, Dolph L: 3 articles (09/2014 - 05/2006)|
|7.||Holmgren, Arne: 3 articles (05/2010 - 04/2006)|
|8.||Lu, Jun: 3 articles (05/2010 - 04/2006)|
|9.||Li, Liang: 3 articles (01/2005 - 07/2003)|
|10.||Xie, Yang: 3 articles (01/2005 - 07/2003)|
10/01/2012 - "Recent studies have elucidated that TrxR was upregulated in many malignant tumors and inhibition of TrxR could prevent the tumor initiation and progression, suggesting TrxR to be a promising target for cancer therapy and the high nucleophilic and accessible selenocysteine (Sec) active site might be the prime target for drug design. "
01/01/2014 - "GPx-1 is an anti-oxidant, selenocysteine containing enzyme implicated in several diseases, including cancer, due to the association of specific alleles with disease risk. "
08/17/2012 - "Here we describe a conceptually unique class of biAbs in which the tumor cell specificity of a humanized antibody fragment that recognizes CD3 on T cells is chemically programmed through a C-terminal selenocysteine (Sec) residue. "
05/01/2011 - "Se-methyl-L-selenocysteine (MSC), a naturally occurring organoselenium compound, has shown cancer chemopreventive activity against several types of cancer. "
03/01/2011 - "Trx, which is over-expressed in many human tumors, is a selenocysteine-containing protein associated with cell proliferation and apoptosis inhibition. "
05/27/2015 - "Se-Methyl-L-selenocysteine Induces Apoptosis via Endoplasmic Reticulum Stress and the Death Receptor Pathway in Human Colon Adenocarcinoma COLO 205 Cells."
02/06/1996 - "The selenocysteine-containing TR from the adenocarcinoma cells may be a variant form distinct from rat liver TR."
01/01/2002 - "Recent studies with a human adenocarcinoma cell line led to the unexpected discovery that selenocysteine occurs in mammalian thioredoxin reductase. "
|3.||Body Weight (Weight, Body)
11/01/2014 - "In this study, three organoseleniums: selenocysteine (Sec), Se-methyl-selenocysteine (MSeCys), and SeMet and two inorganic Se species: selenate and selenite were determined and quantified in the blood at different post-intubation periods (12, 24, 48h) and in the muscle, liver, and kidneys at 48h in white sturgeon orally intubated with a single dose of control (carrier), SeMet (500μg Se/kg body weight; BW), MeHg (850μg Hg/kg BW), and both (Se+Hg; at 500μg Se/kg and 850μg Hg/kg BW). "
|4.||Contagious Ecthyma (Orf)
03/01/2013 - "Apart from the wild-type human Sep15 gene fragment, two Sep15 recombinants were constructed containing Sep15 open reading frame (ORF) and the selenocysteine insertion sequence (SECIS) element from either human Sep15 or C. "
09/01/2012 - "The 1135 bp full-length cDNA contains a 9 bp 5'-untranslated region (UTR), an open reading frame (ORF) of 564 bp encoded a deduced protein of 187 amino acids (aa), and a 562 bp 3'-UTR with a 100 bp conserved eukaryotic selenocysteine insertion sequence (SECIS). "
01/01/2012 - "The 1582-bp cDNA contained an open reading frame (ORF) of 1248 bp, a 103-bp 5'-untranslated region (UTR), and a 231-bp 3'-UTR, which contained a conserved selenocysteine insertion sequence (SECIS) element, a conventional polyadenylation signal, and a poly A tail. "
09/01/2010 - "The 1321-bp cDNA contained an open reading frame (ORF) of 564bp, a 69-bp 5'-untranslated region (UTR), and a 688-bp 3'-UTR containing a poly A tail and a conserved selenocysteine insertion sequence (SECIS) element. "
01/01/2010 - "However, it is still difficult to identify the open reading frame (ORF) of eukaryotic selenoprotein gene, because the TGA codon for a selenocysteine (Sec) residue in the active centre of selenoprotein is traditionally a terminal signal of protein translation. "
|5.||African Trypanosomiasis (Nagana)
10/31/2008 - "Trypanosoma brucei, the causative agent of African sleeping sickness, encodes three cysteine homologues (Px I-III) of classical selenocysteine-containing glutathione peroxidases. "
08/01/2007 - "Trypanosoma brucei, the causative agent of African sleeping sickness, encodes three nearly identical genes for cysteine-homologues of the selenocysteine-containing glutathione peroxidases. "
04/15/2005 - "Trypanosoma brucei, the causative agent of African sleeping sickness, encodes three nearly identical cysteine homologues of the classical selenocysteine-containing glutathione peroxidases. "
02/28/2003 - "Trypanosoma brucei, the causative agent of African sleeping sickness, has three nearly identical genes encoding cysteine homologues of classical selenocysteine-containing glutathione peroxidases. "
|3.||Transfer RNA (tRNA)
|5.||Sodium Selenite (Selenite)
|9.||selenic acid (selenate)
|10.||Aligeron (AS 2)
|1.||Heterologous Transplantation (Xenotransplantation)