A hereditary disease caused by autosomal dominant mutations involving CHROMOSOME 19. It is characterized by the presence of INTESTINAL POLYPS, consistently in the JEJUNUM, and mucocutaneous pigmentation with MELANIN spots of the lips, buccal MUCOSA, and digits.
Also Known As:
Polyposis, Hamartomatous Intestinal; Polyps-and-Spots Syndrome; Syndrome, Peutz-Jeghers; Lentiginosis, Perioral; Periorificial Lentiginosis Syndrome; Peutz-Jegher's Syndrome; Peutz-Jeghers Polyposis; Hamartomatous Intestinal Polyposes; Hamartomatous Intestinal Polyposis; Intestinal Polyposes, Hamartomatous; Intestinal Polyposis, Hamartomatous; Lentiginoses, Perioral; Perioral Lentiginoses; Perioral Lentiginosis; Periorificial Lentiginosis Syndromes; Peutz Jegher's Syndrome; Peutz Jeghers Polyposis; Peutz Jeghers Syndrome; Peutz-Jegher Syndrome; Polyposes, Hamartomatous Intestinal; Polyposis, Peutz-Jeghers; Polyps and Spots Syndrome; Polyps-and-Spots Syndromes; Syndrome, Periorificial Lentiginosis; Syndrome, Peutz-Jegher's; Syndrome, Polyps-and-Spots; Syndromes, Periorificial Lentiginosis; Syndromes, Polyps-and-Spots