Gout Suppressants (Antigout Agents)

Agents that increase uric acid excretion by the kidney (URICOSURIC AGENTS), decrease uric acid production (antihyperuricemics), or alleviate the pain and inflammation of acute attacks of gout.

Also Known As:

Networked: 63 relevant articles (4 outcomes, 13 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kim, Dong-Seon: 2 articles (01/2022 - 09/2021)
2.	Sung, Yoon-Young: 2 articles (01/2022 - 09/2021)
3.	Chen, Ke-Li: 2 articles (01/2018 - 01/2017)
4.	Deng, Guang-Rui: 2 articles (01/2018 - 01/2017)
5.	Li, Juan: 2 articles (01/2018 - 01/2017)
6.	Zhang, Guo-Li: 2 articles (01/2018 - 01/2017)
7.	Zhao, Ping: 2 articles (01/2018 - 01/2017)
8.	Borghi, Claudio: 2 articles (06/2015 - 05/2015)
9.	Cicero, Arrigo F G: 2 articles (06/2015 - 05/2015)
10.	D'Addato, Sergio: 2 articles (06/2015 - 05/2015)

Related Diseases

1.	Gout 06/01/2000 - "A proper understanding that this symptom is relieved by antihyperuricemic drugs may serve as additional motivation for gout patients to take their medication regularly." 11/01/2023 - "Therefore, it is particularly suitable for further investigations into the pathogenesis of gout and also serves as a valuable platform for screening potential antigout agents." 06/01/2000 - "Thirty-two gout patients who had received continuous treatment with antihyperuricemic drugs for more than 3 months were selected. " 06/01/2000 - "Gout patients are asymptomatic during intercritical periods, even if they are not receiving antihyperuricemic drugs. " 03/01/1978 - "[Treatment of gout with alternate-day antihyperuricemic drugs (author's transl)]."
2.	Hyperuricemia 09/29/2021 - "This study demonstrates the antihyperuricemic activity of ULP and its potential effect for the treatment of hyperuricemia-related diseases." 01/01/2020 - "Thus, the utilization of SA as an antihyperuricemic agent may have considerable potential for the development of functional foods for the possible treatment of hyperuricemia. " 04/02/2015 - "Thus SQ could be a potent antihyperuricemic agent which can perform as a safer and effective agent in the management of hyperuricemia via regulating the renal transporters." 04/05/2016 - "Our results demonstrate antihyperuricemic effect of novel thiadiazolopyrimidin-5-one analogues in oxonate treated rats, which can be further explored not only as antigout therapeutics but also in other systems where hyperuricemia is the driving cause of the disease." 01/01/2006 - "Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics."
3.	Cardiovascular Diseases (Cardiovascular Disease) 04/01/2016 - "Recently, some small-scale interventional studies on antihyperuricemic medications showed that the latter improved angina symptoms and prevented cardiovascular disease. " 05/01/2015 - "We selected a Brisighella Heart Study cohort sample of 1557 subjects, consecutively visited in the 2004 and 2008 surveys, in a setting of primary prevention for cardiovascular disease and without a known diagnosis of arrhythmia or left ventricular hypertrophy, excluding subjects affected by gout or taking any antihyperuricemic agent or drugs able to interfere with the QT interval. "
4.	Gouty Arthritis 12/01/2000 - "Latent overproductive hyperuricemia increases in patients during the intermittent phase of gouty arthritis under long-term antihyperuricemic treatment." 01/01/2018 - "Corrigendum to "Pharmacological Basis for Use of Selaginella moellendorffii in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition"." 01/01/2017 - "Pharmacological Basis for Use of Selaginella moellendorffii in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition." 06/15/2004 - "A retrospective study of the relationship between serum urate level and recurrent attacks of gouty arthritis: evidence for reduction of recurrent gouty arthritis with antihyperuricemic therapy." 12/01/2019 - "Conclusions: This study demonstrated for the first time that BHA exhibits anti-inflammatory, antioxidative and antihyperuricemic effects in vivo, suggesting a potential therapeutic application of BHA in gouty arthritis and hyperuricemia."
5.	Chronic Renal Insufficiency 05/18/2017 - "The ability of antihyperuricemic therapy to exert renoprotective effects in patients with chronic kidney disease (CKD) is controversial. " 12/01/2011 - "We have retrospectively evaluated the uric acid control status and renal function changes over a period of up to 7 years in 35 patients with renal impairment who had stage 3 or higher chronic kidney disease (CKD; stage 3 in 32 patients, stage 4 in 2 patients, and stage 5 in 1 patient) associated with hyperuricemia and were receiving monotherapy with benzbromarone as an antihyperuricemic drug. " 11/01/2020 - "PubMed MEDLINE, Embase, Web of Science, Scopus, and Cochrane CENTRAL databases were searched from inception to December 2019 using the key terms "allopurinol," "febuxostat," "xanthine oxidase inhibitors," "gout suppressants," "hyperuricemia," "gout," "chronic renal insufficiency," and "kidney transplantation." Studies with follow-up duration ≥ 12 months were included. "

Related Drugs and Biologics

1.	Uric Acid (Urate)
2.	Allopurinol (Remid)
3.	potassium oxonate
4.	Probenecid (Benemid)
5.	Sulfinpyrazone (Anturane)
6.	Creatinine
7.	Adenine
8.	dioscin
9.	Xanthine Oxidase
10.	Capsules (Microcapsules)

Related Therapies and Procedures

1.	Therapeutics
2.	Oral Administration
3.	Kidney Transplantation
4.	Complementary Therapies (Alternative Medicine)
5.	Meditation