Micropeptides

Polypeptides 100 amino acids or less in length that are encoded by SHORT OPEN READING FRAME.

Also Known As:

Peptides, sORF-Encoded; Short ORF Encoded Peptides; Small ORF Encoded Micropeptides; Small ORF Encoded Peptides; lncRNA Encoded Micropeptides; sORF Encoded Micropeptides; sORF Encoded Peptides; smORF Encoded Micropeptides; smORF Encoded Peptides; Microproteins; Short ORF-Encoded Peptides; Small ORF-Encoded Micropeptides; Small ORF-Encoded Peptides; lncRNA-Encoded Micropeptides; sORF-Encoded Micropeptides; sORF-Encoded Peptides; smORF-Encoded Micropeptides; smORF-Encoded Peptides

Networked: 48 relevant articles (1 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Micropeptides: 48
  - mouse 1810058I24Rik protein

Experts

1.	Zhu, Ying: 3 articles (01/2022 - 11/2019)
2.	Zhuang, Shi-Mei: 3 articles (01/2022 - 11/2019)
3.	Li, Mengwei: 2 articles (10/2022 - 01/2020)
4.	Xu, Hanmei: 2 articles (10/2022 - 01/2020)
5.	Liu, Xingguo: 2 articles (01/2022 - 11/2019)
6.	Sang, Ye: 2 articles (01/2022 - 01/2022)
7.	Wang, Feng-Yi: 2 articles (01/2022 - 01/2022)
8.	Xie, Chen: 2 articles (01/2022 - 01/2019)
9.	Li, Bin: 2 articles (01/2021 - 04/2020)
10.	Meng, Yu: 2 articles (11/2019 - 01/2019)

Related Diseases

1.	COVID-19 01/01/2020 - "Detection of urinary microproteins and application of multiple indicators assessment could be helpful for discovering abnormal renal function in patients with COVID-19. "
2.	Neoplasms (Cancer) 12/01/2023 - "The present review mainly highlights the latest studies on ncRNA-encoded micropeptides in different cancers and categorizes them based on their subcellular localization, thereby providing a theoretical basis for micropeptide applications in the early diagnosis and prognosis of cancer and as therapeutic targets. " 11/04/2021 - "This study not only reports a previously unknown function of micropeptides but also provides new opportunities for targeting the translation machinery in cancer cells." 12/01/2023 - "Several micropeptides have been characterized and proven to have various functions in human physiology and pathology, particularly in cancer. " 12/01/2023 - "Subcellular localization and relevant mechanisms of human cancer-related micropeptides." 01/01/2023 - "Recent research has shown that lncRNAs can encode micropeptides that mediate their functions in tumors. "
3.	Hypertension (High Blood Pressure) 07/01/1976 - "[Urinary excretion of microproteins during essential arterial hypertension]." 09/01/2000 - "The purpose of this study was to elucidate the pathophysiological significance of these urinary microproteins as an indicator of cardiovascular organ injuries in hypertension. " 04/01/1991 - "In order to evaluate the influence of glycemic control and hypertension on the development of diabetic nephropathy, we measured urinary excretion of albumin (AER) and other microproteins in non-insulin-dependent diabetes mellitus (NIDDM), and reexamined the 103 patients who had had AER less than 300 micrograms/min at the initial study 12-18 months later. "
4.	Proteinuria 01/01/2013 - "A tubular proteinuria causes an increase in urinary excretion of microproteins. " 11/01/1979 - "The present data suggest that the proteinuria is due to ineffective proximal tubular reabsorption of low molecular weight microproteins as a result of glomerulo-tubular imblance in early life." 01/01/1979 - "By measuring clearances of the microproteins, the proteinuria with this pattern could be established as form independant from glomerular and tubular proteinurias. " 05/15/1975 - "Tubular proteinurias are associated with normal as well as with impaired glomerular filtration, which, in part, might influence the amount of microproteins excreted." 05/15/1975 - "The course of acute tubular diseases reveals proteinurias of different micromolecular composition depending of the improving tubular function; this supports the concept of a selective tubular reabsorption of microproteins. "
5.	Wounds and Injuries (Trauma) 09/01/2000 - "The purpose of this study was to elucidate the pathophysiological significance of these urinary microproteins as an indicator of cardiovascular organ injuries in hypertension. "

Related Drugs and Biologics

1.	Indicators and Reagents (Reagents)
2.	Immunoglobulin G (IgG)
3.	Albumins
4.	Proteins (Proteins, Gene)
5.	Biomarkers (Surrogate Marker)
6.	Peptides (Polypeptides)
7.	Micropeptides
8.	Long Noncoding RNA
9.	RNA (Ribonucleic Acid)
10.	Enzymes

Related Therapies and Procedures

1.	Glycemic Control
2.	Precision Medicine
3.	Therapeutics
4.	Aftercare (After-Treatment)